Essays about: "Chymotrypsin-like protease"

Found 2 essays containing the words Chymotrypsin-like protease.

1. 1. In Vitro Assessment of Novel Compounds as Potential Pan-Coronavirus Therapeutics in SARS-CoV-2 and In Vitro Assessment of a Pan-Flavivirus Compound in Zika Virus

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Julia Berger; [2022]
   Keywords : Human coronavirus; active protease inhibitors; drug discovery; 3CLpro; Zika virus; flavivirus inhibitor; NS2B-NS3;

   Abstract : Through the SARS-CoV-2 pandemic, it has become clear that the development of antivirals is essential for the health and wellbeing of the population. In this study, novel active site protease inhibitors against SARS-CoV-2 were tested for their inhibitory activity against the viral 3-Chymotrypsin like protease through the means of FRET based enzymatic assays. READ MORE

3. 2. X-ray Crystallographic Structure of theMurine Norovirus protease at 1.66 Å Resolutionand Functional Studies of the β-ribbon

   University essay from Institutionen för fysik, kemi och biologi

   Author : Gabriela Baeza; [2011]
   Keywords : virus; polyprotein; Caliciviridae; aggregation; Chymotrypsin-like protease;

   Abstract : In humans, noroviruses (NVs) cause acute epidemic and viral gastroenteritis. NVs do not only infect humans; viruseshave also been found in pigs, cows, sheep, mice and dogs. The focus in this project has been on the murine norovirus(MNV). READ MORE