Essays about: "Peptide descriptors"

Found 3 essays containing the words Peptide descriptors.

  1. 1. Creating a High-Throughput Workflow for Automated Peptide Characterization using LC-MS

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Sara Forsberg; [2023]
    Keywords : High-throughput analysis; Impurity profiling; UHPLC-HRMS; Peptide characterization; Peptide descriptors; Analytical chemistry; Technology and Engineering;

    Abstract : In the early stage of a drug discovery project, there is a need for efficient methods that can analyse peptides in short time. This includes methods that confirm the peptide’s identity and estimates its relative purity in an efficient and reliable way. READ MORE

  2. 2. Benchmarking Machine Learning Methods for Peptide Activity Predictions

    University essay from Göteborgs universitet/Institutionen för data- och informationsteknik

    Author : Boel Knutson; Lida Meskini Moudi; [2022-10-14]
    Keywords : Drug discovery; peptide; classification; molecular representation; Z-scales; pseudo amino acid composition; one-hot representation; random forests; support vector machines;

    Abstract : One of the main challenges in the drug discovery process is to find a suitable compound for further analysis. The compound must affect the target relevant for the specific disease, while at the same time have desired properties to make it a safe and efficient drug candidate. READ MORE

  3. 3. Chromatography of Therapeutic Peptides - Contrasting SFC and HPLC

    University essay from Uppsala universitet/Farmakognosi

    Author : Joakim Bagge; [2019]
    Keywords : ;

    Abstract : This work is a comparison of a well-established and a novel, "green" and efficient technique to separate peptides of pharmaceutical interest. An attempt is made to derive the chromatographic retention behaviour from these techniques to a number of property descriptors derived from the linear sequence of amino acids. READ MORE