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Found 2 essays matching the above criteria.

1. 1. Management and consequences of QT-related risk prescriptions at Uppsala University Hospital

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Julia Holmgren; [2022]
   Keywords : QT prolongation; SAPVAL;

   Abstract : Background: Drugs are an important part of treating diseases but can also come with its risks. To reduce the risks, a system assisted pharmaceutical validation (SAPVAL) is being developed at Uppsala University Hospital. READ MORE

3. 2. Creation of a Next-Generation Standardized Drug Groupingfor QT Prolonging Reactions using Machine Learning Techniques

   University essay from Uppsala universitet/Avdelningen för systemteknik

   Author : Jacob Tiensuu; Elsa Rådahl; [2021]
   Keywords : Pharmacovigilance; Adverse Drug Reactions; MedDRA; VigiBase; WHODrug Global; QT prolongation; Torsades de Pointes; Individual Case Safety Reports; Text Recognition; Standardised Drug Grouping; Multinomial Logistic Regression; BERT;

   Abstract : This project aims to support pharmacovigilance, the science and activities relating to drug-safety and prevention of adverse drug reactions (ADRs). We focus on a specific ADR called QT prolongation, a serious reaction affecting the heartbeat. Our main goal is to group medicinal ingredients that might cause QT prolongation. READ MORE