Essays about: "TRIM21"

Found 3 essays containing the word TRIM21.

  1. 1. Imaging of the Cytosolic Antibody Receptor TRIM21

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Þórunn Stefánsdóttir; [2022]
    Keywords : TRIM21; ProteinStructure; Antibody; cryo-EM; Gel-Filtration SizeExclusion Chromatography ; Immunology; ProteinPurification; SDS-PAGE; TRIM21; Proteinstruktur; Antikroppar; cryo-EM; Gel-filtreringsKromatografi; Immunologi; ProteinRening; SDS-PAGE;

    Abstract : TRIM21 is a cytosolic ubiquitin ligase and an antibody receptor that providesa last line of defense against invading pathogens. By utilizing the diversity ofantibody repertoire to identify pathogens, TRIM21 serves as a link betweenintrinsic cellular defense and adaptive immunity. READ MORE

  3. 2. Profiling the autoantibody repertoire in systemic sclerosis

    University essay from KTH/Proteinvetenskap

    Author : Emmie Pohjanen; [2021]
    Keywords : Systemic sclerosis; rheumatology; autoimmunity; autoantibody; biomarkers; Systemisk skleros; reumatologi; autoimmunitet; autoantikropp; biomarkörer;

    Abstract : Systemisk skleros (SSc) är en autoimmun rheumatisk sjukdom som kännetecknas av fibros i huden och/eller de interna organen, vaskulopati och en autoimmun reaktion från immunförsvaret, med eller utan specifika autoantikroppsprofiler. Diagnostisering och sjukdomsbehandling försvåras av sjukdomens heterogena natur. READ MORE

  4. 3. Ro52 : Structure and interactions of constructs of RING and B-box

    University essay from Linköpings universitet/Teknisk biologi; Linköpings universitet/Tekniska högskolan

    Author : Emmy Österberg; [2014]
    Keywords : Structural biology; Ro52; TRIM21; Ubiquitination; Western blot; Protein expression; Protein purification;

    Abstract : The ubiquitination process is vital to maintain the protein homeostasis in the cell. With high specificity it regulates degradation of proteins by tagging them with a small protein called ubiquitin. Four proteins are involved to perform the process and in this thesis one of these proteins is studied. READ MORE