Essays about: "XTT"

Found 5 essays containing the word XTT.

  1. 1. Filtering of Clinical NGS Data to Improve Low Allele Frequency Variant Calling

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Tomas Cumlin; [2022]
    Keywords : Next-generation sequencing; Variant calling; Clinical sequencing; Substitution error; Cancer sequencing; Error rate; substitution; Somatic mutation;

    Abstract : Massive parallel sequencing (NGS) is useful in detecting and later classifying somatic driver mutations in cancer tumours. False-positive variants occur in the NGS workflow and they may be mistaken for low frequency somatic cancer mutations in a patient sample. READ MORE

  3. 2. Action of CB1 and CB2 antagonists/inverse agonists on mantle cell lymphoma

    University essay from Akademin för hållbar samhälls- och teknikutveckling

    Author : Daniel Chui; [2011]
    Keywords : cannabinoid; mantle; lymphoma; hemopressin; anandamide; thc;

    Abstract : In this study, the effects of antagonists to the cannabinoid receptors in MCL cell lines were studied. Results presented in this study show that signalling through cannabinoid receptor with antagonists such as SR141716, SR144528 decreases cell viability but hemopressin when analyzing with XTT. READ MORE

  4. 3. Effect of oxaliplatin on HCT116 P53+/- colon cancer cells

    University essay from Institutionen för vård och natur

    Author : Asieh Azarm; [2011]
    Keywords : Oxaliplatin; HCT116 P53 -; XTT; Bax; Apoptosis;

    Abstract : Oxaliplatin as an effective chemotherapeutic agent in FOLFOX regimens is using to treat colorectal cancer. In this study we investigate cytotoxicity of Oxaliplatin as single chemotherapeutic agent toHCT116P53+/- to identify molecular mechanism of Oxaliplatin action in induction of apoptosis pathway. READ MORE

  5. 4. Action of CB1 and CB2 antagonists/inverse agonists on mantle cell lymphoma

    University essay from Akademin för hållbar samhälls- och teknikutveckling

    Author : Daniel Chui; [2011]
    Keywords : ;

    Abstract : In this study, the effects of antagonists to the cannabinoid receptors in MCL cell lines were studied. Results presented in this study show that signalling through cannabinoid receptor with antagonists such as SR141716, SR144528 decreases cell viability but hemopressin when analyzing with XTT. READ MORE

  6. 5. Effect of 5-Flourouracil On HCT-116 P53+/- Human Colon Cancer Cells

    University essay from Institutionen för vård och natur

    Author : Sunela Perwaiz; [2011]
    Keywords : ;

    Abstract :  The purpose of this study was to observe the effects of 5-flourouracil on HCT-116 p53 +/- colon cancer cells. In order to investigate the effects of the drug, concentration-dependent assays and time-dependent  assay  procedures  were  used. READ MORE