Essays about: "differential expression"

Showing result 1 - 5 of 52 essays containing the words differential expression.

  1. 1. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    University essay from KTH/Proteinvetenskap

    Author : Alexandra Johannesson; [2023]
    Keywords : neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Abstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE

  3. 2. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Yi Su; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. READ MORE

  4. 3. Quality Control and Differential Analysis Tools for Sequencing Data with User-Friendly GUI Implementation Based on PySimpleGUI

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Mohit Bachan Singh Panwar; [2023]
    Keywords : ;

    Abstract : The paper details the development, implementation and assessment of a suite of bioinformatics tools, namely Adapter Trimmer, Quality Trimmer, Quality Filter  and two Differential Expression Analysis (DEA) tools based on existing libraries like edgeR via rpy2 and PyDESeq2. All these tools are unified within a consolodated graphical user interface (GUI), underscoring the focus on accessibility and user-centric design. READ MORE

  5. 4. Profiling the Blood Proteome in Autoimmune Disease Using Proximity Extension Assay

    University essay from KTH/Proteinvetenskap

    Author : Julia Asp; [2023]
    Keywords : Plasma proteomics; proximity extension assay; autoimmune disease; differential expression; machine learning; biomarkers; Plasma proteomik; proximity extension assay; autoimmuna sjukdomar; differentiellt proteinuttryck; maskininlärning; biomarkörer;

    Abstract : Autoimmuna sjukdomar är en samling komplexa, kroniska, inflammatoriska sjukdomstillstånd som kännetecknas av dysreglering av immunsystemet, vilket resulterar i inflammation och skada av vävnader, celler och organ. Dessa sjukdomar har en betydande inverkan på individens livskvalitet och bidrar ofta till ökad dödsrisk där komorbiditeter föreligger. READ MORE

  6. 5. Dual RNA-seq analysis of gene co-expression and immune response mechanisms in chickens infected by Eimeria tenella

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Alma Hansen; [2023]
    Keywords : RNA-seq; Eimeria; bioinformatics; gene co-expression;

    Abstract : Coccidiosis caused by Eimeria parasites is a worldwide problem, affecting chickens and leading to great losses in the poultry industry. Current vaccines are costly and non-optimal, and the parasite has developed resistance to the anticoccidials in use. READ MORE