Essays about: "genotype"

Showing result 1 - 5 of 118 essays containing the word genotype.

  1. 1. Development of a novel quantitative PCR analysis method for HIV-1

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Teoretisk kemi

    Author : Anna-Malin Hallberg; [2021]
    Keywords : HIV; PCR; primers; probes; virus; detection; blood plasma; pathogen; biological pharmaceutical; protein-based pharmaceutical; genotype; subtype; RT qPCR; extraction; TaqMa; RNA virus; cross-dimer; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering; Chemistry;

    Abstract : Biological pharmaceuticals are the answer to many severe diseases of today’s society. Some of these are protein-based drugs and can be produced from human blood plasma. In order to guarantee the safety of patients, absence of any pathogens needs to be ensured. READ MORE

  2. 2. Generation of induced pluripotent stem cells (iPSCs) lines deficient for genes associated with neurodevelopmental diseases using CRISPR/Cas9 technology

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Claudia De Guidi; [2021]
    Keywords : ;

    Abstract : Induced pluripotent stem cells (iPSCs) can self-renew and differentiate into many other cell types. IPSCs are derived from somatic cells, and upon reprogramming, they share an expression profile similar to embryonic stem cells (ESCs). READ MORE

  3. 3. Optimisation of autoencoders for prediction of SNPs determining phenotypes in wheat

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildningUppsala universitet/Institutionen för informationsteknologi

    Author : Karthik Nair; [2021]
    Keywords : Deep Learning; Machine Learning; Convolutional Neural Networks; Convolutional Variational Autoencoders; Autoencoders; SNP-Phenotype relationships; Genetics; Agricultural Bioinformatics; Neural Networks; Unsupervised Learning;

    Abstract : The increase in demand for food has resulted in increased demand for tools that help streamline plant breeding process in order to create new varieties of crops. Identifying the underlying genetic mechanism of favourable characteristics is essential in order to make the best breeding decisions. READ MORE

  4. 4. Advanced Detection Methods of Genomic Barcodes for Genotyping Escherichia coli Libraries

    University essay from Uppsala universitet/Institutionen för cell- och molekylärbiologiUppsala universitet/Institutionen för biologisk grundutbildning

    Author : Nicole Eger; [2021]
    Keywords : Genotyping; Genomic barcodes; LAMP; PNA; RCA; FISH;

    Abstract : Pooled cell strain libraries are a powerful tool allowing to investigate the influence of genetic modifications on phenotypes in high throughput single-cell assays. To link the genotype to phenotype in each cell of the library, unique 20 base pairs (bp) long barcodes are used to allow in situ genotyping after phenotyping via fluorescence microscopy. READ MORE

  5. 5. Analysis of a Filifactor Alocis genotype and its effect on pathological progress in periodontitis

    University essay from Umeå universitet/Tandläkarutbildning; Umeå universitet/Tandläkarutbildning

    Author : Jessica Radu; Kati Heinämäki; [2021]
    Keywords : ;

    Abstract : Background: Filifactor alocis is a gram positive, obligate anaerobic rod bacterium that has shown correlation to pathogenic events that may be linked to periodontitis. Previous studies have proved the presence of so-called “rtx” toxins in F. alocis that are similar to the leukotoxin of A. actinomycetemcomitans. READ MORE