Essays about: "miR-34a"

Found 3 essays containing the word miR-34a.

  1. 1. Investigations of miR-34a structure and dynamics by SHAPE MaP and optimal time between transfection and modification by qPCR

    University essay from KTH/Proteinvetenskap

    Author : Ellinor Lindén; [2023]
    Keywords : SHAPE MaP; qPCR; miRNA; HNF4α; mRNA-34a; SHAPE MaP; qPCR; miRNA; HNF4α; mRNA-34a;

    Abstract : microRNA (miRNA) är korta icke-kodande RNA sekvenser som har fått ökande uppmärksamhet då de kan binda till mRNA och styra vårt genuttryck. Omkring trettio procent av våra proteinkodande gener styrs av miRNA. miRNA binder till mRNA vilket hindrar dess translation eller leder till nedbrytning av mRNA. READ MORE

  3. 2. Designing strategies to induce miRNA strand selection

    University essay from Uppsala universitet/Polymerkemi

    Author : Cecilia Ålander; [2018]
    Keywords : microRNA miRNA MiR-34a strand selection;

    Abstract : .... READ MORE

  4. 3. Structural elucidation of mRNA(Sirt1)-microRNA 34a complex

    University essay from KTH/Skolan för teknikvetenskaplig kommunikation och lärande (ECE)

    Author : Mona Farshchian; [2015]
    Keywords : mRNA Sirt1 ; miR-34a; in vitro transcription; gel electrophoresis; CD spectroscopy; NMR; cancer regulation via p53; HPLC; mRNA Sirt1 ; miR-34a; in vitro transkription; gel elektroforesis; CD spektroskopi; NMR; cancer regulering via p53; HPLC;

    Abstract : The aim of this thesis is to understand RNA-RNA interactions steering cellular functions, as in the case of this thesis the structure of mRNA(Sirt1) in complex with microRNA-34a (miR-34a). MiR-34a regulates the cancer protein p53 via Sirt1 modulation. READ MORE