Essays about: "protein dynamics"

Showing result 21 - 25 of 65 essays containing the words protein dynamics.

  1. 21. Extraction of gating mechanisms from Markov state models of a pentameric ligand-gated ion channel

    University essay from KTH/Proteinvetenskap

    Author : Dimitrios Karalis; [2021]
    Keywords : GLIC; Markov state models MSMs ; KL divergence; Machine Learning ML ; pentameric ligand-gated ion channel pLGIC ; channel gating;

    Abstract : GLIC är en pH-känslig pentamerisk ligandstyrd jonkanal (pLGIC) som finns i cellmembranet hos prokaryoten Gloeobacter violaceus. GLIC är en bakteriell homolog till flera receptorer som är viktiga i nervsystemet hos de flesta eukaryotiska organismer. READ MORE

  3. 22. Sustaining Orientation of Ubiquitin for Single Particle Imaging Using Electric Fields

    University essay from Uppsala universitet/Kemisk och biomolekylär fysik; Uppsala universitet/Energimaterialens fysik

    Author : Adi Bijedic; [2021]
    Keywords : ;

    Abstract : Single-particle imaging, or SPI, is a method used to obtain the three-dimensional structure of particles. Repeatedly aiming X-rays at samples of a particle produces diffraction patterns, which are combined to a best-fit three-dimensional model of the particle. SPI of proteins can be improved by orienting the protein before imaging. READ MORE

  4. 23. Study of fibrillation processes of amyloid-like β-lactoglobulin protein

    University essay from KTH/Kemi

    Author : Jose Nixon; [2021]
    Keywords : bLG; Thioflavin-T Fluroscence; Fibrillation; bLG; Thioflavin-T fluroscens; fibrillering;

    Abstract : Bovint β-laktoglobulinprotein (bLG) är ett litet globulärt protein med 162 aminosyrarester, som vanligtvis finns i mjölkvassle. Under sura förhällanden dissocierar dessa dimera proteiner och bildar amyloidliknande fibriller. READ MORE

  5. 24. Evaluating a coarse-grained IDP-model for structure and dynamics

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Louise Kalander; [2021]
    Keywords : IDP; Intrinsically disordered proteins; Histatin 5; Simulation; Biophysical chemistry; Chemistry;

    Abstract : In this study a coarse-grained model of intrinsically disordered proteins (IDPs) is evaluated to determine whether the model is suitable to use for analyzing the structure and dynamics of IDPs. IDPs are proteins that lack a stable tertiary structure which gives them a flexible structure. READ MORE

  6. 25. Characterization of Alcohol Modulation of a Pentameric Ligand-gated Ion Channel with Electrophysiology and Molecular Dynamics Simulations

    University essay from KTH/Tillämpad fysik

    Author : Sabina Gutheim; [2021]
    Keywords : Biophysics; Electrophysiology; MD simulations; Ligand-gated ion channels; GLIC; Ethanol modulation; Biofysik; Elektrofysiologi; MDsimuleringar; Pentameriska ligandstyrda jonkanaler; GLIC; Etanolmodulering;

    Abstract : Pentameric ligand-gated ion channels (pLGICs) are membrane receptors that play a crucial role in every living organism. The pLGIC protein structure forms a pore through the membrane of a cell that can let specific ions pass through, upon activation by endogenous agonists. READ MORE