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Showing result 1 - 5 of 10 essays matching the above criteria.
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1. Characterization of the role of RbfA and KsgA in ribosome function
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Ribosome biogenesis is the maturation and accurate assembly of ribosomal RNA and proteins to form functional ribosomes competent to enter the translation cycle, facilitated by the action of ribosome biogenesis factors. RbfA and KsgA are two factors involved in late stages of the 30S subunit biogenesis, yet before translation initiation. READ MORE
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2. The role of 6C RNA in gene regulation in mycobacteria
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : The Actinomycetes, to which the Mycobacterium genus belongs contains many pathogens, such as Mycobacterium tuberculosis, which can cause tuberculosis, so it has become a focus area in modern molecular biology research. Mycobacteria contain many proteins and regulatory factors, including tRNA, ncRNA and sRNA, which can help bacteria better adapt to the environment. READ MORE
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3. Fidelity of protein synthesis using sequence reconstructed ancient Elongation Factor Tu
University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för cell- och molekylärbiologiAbstract : To maintain a healthy growth rate of living cells, protein synthesis must take place accurately and efficiently. Translation, the core step decoding the genetic information, governs both fidelity and efficiency. READ MORE
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4. Study of co-translational folding of E. coli dihydrofolate reductase using fluorescence resonance energy transfer (FRET)
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : In prokaryotes, protein synthesis and folding are often coupled, and the protein begins to fold from the N-terminus as it is being synthesized. It has been hypothesised that there could be kinetic coupling of the speed of translation and the folding, which means that an altered rate of synthesis can cause a possible misfolding of the protein. READ MORE
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5. Improving unnatural amino acid mutagensis efficiency and selectivity in mammalian cell
University essay from KTH/Skolan för bioteknologi (BIO)Abstract : Genetically encoded, site-specific incorporation of unnatural amino acids (UAA)into proteins through selective recoding of an amber stop codon provides apowerful route for expressing synthetic proteins in living cells. Recoding of theamber stop codon is achieved by introducing an amber suppressortRNA/synthetase pair orthogonal to the endogenous tRNA complement intocells. READ MORE
