Essays about: "co-translational folding"
Found 2 essays containing the words co-translational folding.
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1. Single-particle tracking for direct measurements of Trigger Factor ribosome binding in live cells
University essay from Uppsala universitet/MolekylärbiologiAbstract : Trigger Factor (TF) is a prokaryotic chaperone protein that exerts its major chaperone activity while associated with translating ribosomes, assisting de novo folding of the emerging nascent chain. Although much is known about the kinetics behind TF-ribosome binding, most results are based on in vitro experiments which fail to mimic the cellular environment. READ MORE
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2. Study of co-translational folding of E. coli dihydrofolate reductase using fluorescence resonance energy transfer (FRET)
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : In prokaryotes, protein synthesis and folding are often coupled, and the protein begins to fold from the N-terminus as it is being synthesized. It has been hypothesised that there could be kinetic coupling of the speed of translation and the folding, which means that an altered rate of synthesis can cause a possible misfolding of the protein. READ MORE
