Essays about: "Gyrolab"

Showing result 1 - 5 of 15 essays containing the word Gyrolab.

1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Sam Vadi Dris; [2024]
   Keywords : Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

   Abstract : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. READ MORE

3. 2. Development of specific host cell protein assays

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Anna Ivert Nordén; [2023]
   Keywords : Gyrolab; Immunoassay; HCP;

   Abstract : The manufacturing and the development of biotherapeutic drugs involves the expression of biotherapeutic proteins in a host cell expression system followed by a purification process. Bioanalytical methods to measure impurities such as host cell proteins (HCPs) are needed to obtain a robust process and a safe drug according to regulatory requirements. READ MORE

4. 3. Increased system sensitivity using fluorescent based immunoassays on the Gyrolab® platform

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Gabriel Lisra; [2023]
   Keywords : Gyrolab; fluorescence; sensitivity; immunoassays;

   Abstract : Immunoassays have become an essential tool in several fields of bioanalytics with tremendous advances in sensitivity and formats seen through the last three decades. Many diseases are today diagnosed solely based on biomarker concentrations evaluated through immunoassays. READ MORE

5. 4. Signal amplification in a microfluidic immunoassay system via Binding Oligo Ladder Detection : Applying the Exazym® signal amplification to the Gyrolab® platform

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Daniel Wiman; [2023]
   Keywords : immunoassay; ultra-sensitive; signal amplification; Gyrolab; Exazym; high sensitivity; microfluidics; BOLD amplification; nucleic acid polymerisation;

   Abstract : Immunoassays are analytical methods that use the highly specific binding of antibodies in order to detect and quantify an analyte. The technique has become a staple in modern biopharmaceutical research and diagnostics, however the measurement of biomarkers like dysregulated cytokines require ultra-sensitive immunoassays that can detect molecules at sub pg/mL concentrations. READ MORE

6. 5. Development of immunoassays that can assess therapeutic bispecific antibodies on the Gyrolab platform

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Ella Hellberg; [2023]
   Keywords : ;

   Abstract : .... READ MORE