Essays about: "lab-on-a-chip"

Showing result 1 - 5 of 12 essays containing the word lab-on-a-chip.

  1. 1. Microfluidic flow splitter shape optimization for high throughput

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Christoffer Papamoustos Palmér; Joel Linder; [2023]
    Keywords : Genetic algorithms; Lab-on-a-chip; Optimization; Acoustofluidics; Microfluidics; Technology and Engineering;

    Abstract : Due to an increasing incidence rate, the need for new effective methods for diagnosing cancer are of high importance. Studies have shown that circulating tumor cells, CTCs, have great potential as a diagnostic biomarker. Acoustophoresis is a label free method, capable of separating CTCs from red blood cells in a blood sample. READ MORE

  2. 2. Robust and Biocompatible Bonding of Hybrid Microfluidic Devices Using Off-Stoichiometric Thiol-ene Thermosets

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Peter Harris; [2023]
    Keywords : OSTE; OSTE ; Microfluidics; Thermoset; Bonding; Thermoplastics; Biocompatibility; OSTE; OSTE ; Mikrofluidik; Härdplast; Binding; Termoplaster; Biokompatibilitet;

    Abstract : Some of the major obstacles the microfluidics industry has yet to overcome in order to facilitate large scale manufacturing of devices are costly back-end processes. Among these, bonding presents some of the most obvious difficulties and is often associated with structural deformation and surface modification. READ MORE

  3. 3. Design improvements for an Organ-on-chip system : Implementation and evaluation of a bubble trap

    University essay from Uppsala universitet/Institutionen för materialvetenskap

    Author : Albin Jonasson; Linnéa Soto Carlsson; [2022]
    Keywords : Organ-on-chip; Microfluidics; Lab-on-chip; Lab-on-a-chip; bubble trap; epithelial; endothelial; cells; biomedical engineering; chip; TEER; Mikrofluidik; labb-på-chip; organ-på-chip; medicinsk teknik; medicinteknik; TEER; bubbelfälla; epitelceller; endotelceller;

    Abstract : The field of organ-on-chip is a relatively new area of research and builds upon the principle of engineering microfluidic systems to mimic the body’s internal environment as precisely as possible. Eventually these models could hopefully simulate whole organ-systems and enable the examination of the cell’s or organ’s reaction to foreign substances like new pharmaceuticals in a better way than current models. READ MORE

  4. 4. Adapting FDM 3D-printing for the manufacture of microfluidic devices

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Oskar Andersson; [2021]
    Keywords : 3D-printing; addative manufacturing; fused deposition modelling; FDM; fused filament fabrication; FFF; microfluidics; microfluidic devices; lab-on-a-chip; microchannels; micro-channels; resolution; settings; Technology and Engineering;

    Abstract : Microfluidic devices have so far not seen widespread use, even though they could potentially be cheaper, better and faster than traditional methods. A possible reason for this is the lack of a middle step between one-of-a-kind experimental devices and cheap mass produced devices. READ MORE

  5. 5. Improving cell secretome analysis and bacteria evolution by means of acoustophoresis

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Moritz Leuthner; [2020]
    Keywords : acoustophoresis; acoustofluidic; lab-on-a-chip; acoustic streaming; acoustic radiation force; particle trapping; particle washing; bulk acoustic waves; BAW; media exchange; cell manipulation;

    Abstract : In both, cell secretome analysis and bacteria evolution, controlled handling of particles with a few to sub-micrometers in size and media exchange are inevitable in order to investigate body fluid’s proteins or change the surrounding culture conditions for pivoted evolution. Typically, nanofiltration and ultra-centrifugation are employed which can lead to cell damage, need large sample volumes and have a high sample loss. READ MORE