Essays about: "mTOR"

Showing result 1 - 5 of 8 essays containing the word mTOR.

  1. 1. The role of salt inducible kinases in the regulation of the mammalian target of rapamycin pathway in adipocytes

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Sulochana Kotresh Jali; [2020]
    Keywords : Biology and Life Sciences;

    Abstract : Salt inducible kinase 2 (SIK2) is found abundantly in adipose tissue and may have a role in the development of diabetes. SIK2 is downregulated in insulin-resistant and obese individuals, thereby providing a new potential target for therapeutic solutions. READ MORE

  3. 2. The effects of NOX2 and NOX4 inhibitors on panc-1 cell viability

    University essay from Högskolan i Skövde/Institutionen för hälsovetenskaper

    Author : Karl-Hermann Sielinou Kamgang; [2020]
    Keywords : ;

    Abstract : Pancreatic cancer is a leading cause of cancer related deaths worldwide and has a low survival rate 1 year after diagnosis. It is therfore important to identify new biomarkers and treatments to improve disease outcome. This experiment investigated the effects of different NOX2 and NOX4 inhibitors on Panc-1 cell lines. READ MORE

  4. 3. Effects of Resistance Training with Heat Stress on Muscle Mass, Strength and Performance

    University essay from Högskolan i Halmstad/Akademin för ekonomi, teknik och naturvetenskap

    Author : Sean Drew; [2019]
    Keywords : Heat; Heat stress; Heat shock protein; Muscle mass; Resistance training; Hypertrophy; mTOR; Hot environment; Performence;

    Abstract : Background: Recent research has demonstrated the presence of heat being an effective stimulus for increasing skeletal muscle and strength. The exposure of increased environmental temperature combined with resistance training has been shown to amplify muscle adaptation for hypertrophy and strength. READ MORE

  5. 4. Do different levels of lactate have an impact on mTORC1-signal and protein synthesis induced by resistance exercise?

    University essay from Gymnastik- och idrottshögskolan, GIH/Institutionen för idrotts- och hälsovetenskap

    Author : Rasmus Liegnell; [2018]
    Keywords : mtorc1; lactate; hypertrophy; muscle cell; resistance exercise;

    Abstract : Aim: To investigate the role of lactate as a potential signaling molecule, for the molecular mechanisms underlying acute resistance exercise adaptation in the muscle cell.    Method: Four women and four men recruited to perform two trials of unilateral leg extension exercise performed with either an infusion of sodium lactate or isotonic saline (placebo), in a randomized, blinded, crossover fashion. READ MORE

  6. 5. Amino acid deprivation of the hypothalamic cell-line N25/2 induces changes in regulation of numerous transporters from the SLC family

    University essay from SLU/Dept. of Microbiology

    Author : Tauseef Ahmad; [2015]
    Keywords : solute carriers; amino acid starvation; mTOR Pathway; AAR Pathway; amino acid transport systems; membrane transport proteins; amino acid transporters;

    Abstract : Amino acids are the building blocks of proteins. They are essential for cell survival and normal cellular functions as they are the key precursors to numerous cellular pathways and processes. Availability of amino acids exhibit vital role in regulation of gene expression in all mammalian cells. READ MORE