Essays about: "receptor desensitization"

Found 5 essays containing the words receptor desensitization.

  1. 1. Characterization of diazepam binding inhibitor as a structure-function tool for human ɣ-aminobutyric acid-A receptors

    University essay from KTH/Proteinvetenskap

    Author : Szabolcs Simon-Guth; [2023]
    Keywords : γ-Aminobutyric acid sub-type A receptors; diazepam binding inhibitor; receptor modulation; recombinant protein expression; two-electrode voltage clamp; dose-response curve; Gammaaminosmörsyrareceptor typ A; Diazepambindande hämmare; receptormodulering; reckmbinant proteinexpression; spänningsklämma med två elektroder; dosresponskurva;

    Abstract : Gammaaminosmörsyrareceptorer typ A (GABAAR) är pentameriska ligandstyrda kloridkanaler som uppvisar neurohämmande egenskaper. Därmed är de primära läkemedelsmål för flera ångestdämpande och lugnande läkemedel som används för att minska förekomsten av aktionspotential i neuroner. READ MORE

  3. 2. Arthrogryposis in calves

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Alexandra Odevall; [2016]
    Keywords : Artrogrypos; kalv; nöt; medfödd missbildning; Crooked Calf Disease; lupiner; lupinus; alkaloider; anagyrine; Arthrogryposis; calf; bovine; congenital deformity; lupines; alkaloids;

    Abstract : Arthrogryposis is a common congenital malformation in cattle and it affects the limbs through fibrosis of the joints leading to fixation. This is due to paralysis of the fetus because of alkaloid toxicosis in the pregnant dam during gestation day 40-70. When the fetus cannot move, the fibrosis develops in the joints and the extremities are fixated. READ MORE

  4. 3. On the Modelling of Kainate Receptor Channels

    University essay from KTH/Matematik (Avd.)

    Author : Tahar Etienne Nabil; [2014]
    Keywords : ;

    Abstract : Kainate receptor channels are a class of ion channels found on the membrane of nerve cells. These proteins play a key role in the brain, since their properties regulate the strength of the synapses. READ MORE

  5. 4. Role of TRPV1 channel and P2Y1 receptor in Ca2+ signalling in β-cells : A study by single cell microfluorometry

    University essay from Institutionen för fysik, kemi och biologi

    Author : Kalaiselvan Krishnan; [2011]
    Keywords : Insulin exocytosis; P2Y1; tolbutamide; ADPr; microfluorometry; Islets of langerhans; β-cells; calcium signaling; signal transduction.;

    Abstract : Increase in the cytoplasmic Ca2+ concentration ([Ca2+]i) in the β-cells triggers insulin exocytosis. Among the Ca2+ channels present in the plasma membrane, the transient receptor potential (TRP) channels receptors are currently of great interest. READ MORE

  6. 5. Thrombin receptor signalling in platelets: PAR1, but not PAR4, is rapidly desensitized

    University essay from Institutionen för fysik, kemi och biologi

    Author : Linda Haglund; [2009]
    Keywords : Nitric oxide; PAR1; PAR4; platelets; receptor desensitization;

    Abstract : Platelets play a key role in primary haemostasis but are also related to the pathogenesis of arterial thrombosis. Thrombin is the most effective agonist inducing platelet activation. Human platelets express two G-protein coupled thrombin receptors (GPCRs), called protease activated receptor (PAR)1 and PAR4. READ MORE