Essays about: "transkriptionsfaktor"

Showing result 1 - 5 of 6 essays containing the word transkriptionsfaktor.

1. 1. Effekterna av vitamin D-metaboliter på tunikamycin-inducerad ER-stress i PC3- och NSC34-celler

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Ida Malo; [2023]
   Keywords : ;

   Abstract : Bakgrund: Vitamin D är ett steroidvitamin och tillförs oss från vissa livsmedel eller syntetiseras när vår hud utsätts för solen. Inuti cellerna fungerar det som en transkriptionsfaktor för en grupp gener. READ MORE

3. 2. Hic2 overexpression increase of cell reprogramming efficiency- a computational study

   University essay from Lunds universitet/Fysiska institutionen; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

   Author : Paulina Ibek; [2023]
   Keywords : Physics and Astronomy;

   Abstract : Since stem cells have many applications in medicine and can be used for treating e.g. cancer and diabetes, finding efficient methods for producing them is a relevant area of research. READ MORE

4. 3. Binuclear zinc transcription factors and the regulation of patulin biosynthesis in the filamentous Ascomycete Penicillium expansum

   University essay from Lunds universitet/Bioteknik (master)

   Author : Robert Hansen Jagrelius; [2021]
   Keywords : secondary fungal metabolism; penicillium expansum; patulin; binuclear zinc transcription factors; dimerization; deepcoil; Biology and Life Sciences;

   Abstract : This thesis investigated the regulation of patulin production in Penicillium expansum in relation to fungal global regulators as well as the cluster-specific binuclear zinc transcription factor (BZTF) patL in silico. It also explored the state of BZTF research in filamentous ascomycetes fungi, and questioned if results in Saccharomyces cerevisiae can be freely translated to other taxonomic groups. READ MORE

5. 4. Purification, functional characterization and crystallization of the PerR peroxide sensor from Saccharopolyspora erythraea

   University essay from Uppsala universitet/Strukturbiologi

   Author : Grim Elison Kalman; [2019]
   Keywords : structural biology; cell culture; protein expression; genetic engineering; spectroscopy; X-ray crystallography; small angle X-ray scattering; SAXS; transcription factor; PerR; metal binding; antibiotics; Saccharopolyspora erythraea; S. erythraea; soil bacterium; actinobacteria; actinomycetes; oxidative stress; peroxide stress; structure determination; characterization; stabilization; peroxide sensor; iron sensor; manganese sensor; metalloprotein; metal ion homeostasis; metal ion; prokaryotic; strukturbiologi; cellodling; proteinuttryck; genteknik; spektroskopi; röntgenkristallografi; småvinkel-röntgenspridning; SAXS; transkriptionsfaktor; PerR; metallbindande; antibiotika; Saccharopolyspora erythraea; S. erythraea; jordartsbakterie; Aktinobakterier; Actinobacteria; Actinomycetes; oxidativ stress; peroxid stress; strukturbestämning; karaktärisering; stabilisering; peroxidsensor; järnsensor; mangansensor; metalljonshomeostas; metalljoner; prokaryot;

   Abstract : This report summarizes the work on the cloning, expression, and purification of PerR, a metal sensing regulator from Saccharopolyspora erythraea and the subsequent characterization using small angle X-ray scattering and other biochemical methods. The report aims to provide an insight into prokaryotic metal homeostasis, provide a better understanding of how PerR works and provide valuable information for the continued work on the crystallization of PerR. READ MORE

6. 5. Mus som modelldjur för mutationer i p53

   University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

   Author : David Melin; [2012]
   Keywords : p53; transgena möss; tumör-suppressor; tumöruppkomst; musmodeller;

   Abstract : p53 är en transkriptionsfaktor som gör att celler går i apoptos eller undviker cellproliferation vid DNA-skada. Genen inhiberar bl.a. CDK-komplexet och får på så sätt cellcykeln att avstanna i G1-fasen. READ MORE