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  1. 1. Investigation of endogenous p21 expression and its correlation to therapy resistance in high-risk neuroblastoma

    University essay from KTH/Proteinvetenskap

    Author : Agnes Sorteberg; [2021]
    Keywords : p21; high-risk neuroblastoma; small molecular inhibitor; chemo-resistance; combination treatment;

    Abstract : Neuroblastoma (NB) is a childhood cancer with a highly complex nature. High-risk NB patients undergo intensive treatment regimens that are often followed by long-term side effects. This, in addition to the emergence of resistant cancer cells, highlights a need for novel therapeutic targets and treatment strategies to improve outcome in NB. READ MORE