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  1. 1. Deciphering the ontogeny of unmutated and mutated subsets of Chronic Lymphocytic Leukemia

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Ahmed Mohamed; [2019]
    Keywords : CLL; NGS; mutated CLL; unmutated CLL; CD27 bright; CD27 dull; memory B cell; RNA-sequencing;

    Abstract : Chronic Lymphocytic Leukemia (CLL) is a type of cancer that affects the B cells of the immune system causing problems in the process of producing antibodies. It can be sorted into mutated and unmutated CLL based on the percentage of somatic mutations in the Immunoglobulin Heavy chain Variable region (IgHV). READ MORE