Essays about: "Galectin-3 inhibitor"

Found 3 essays containing the words Galectin-3 inhibitor.

  1. 1. Design, synthesis, and evaluation of 1-phenylethanol and C2 threitol derivatives as non-pyranose galactose-mimicking inhibitors of Galectin-3

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Qrystal Cruz Giron; [2023]
    Keywords : Galectin-3; Galectin-3 inhibitor; 1-phenylethanol; C2 threitol derivative; galactose-mimicking inhibitor; organic chemistry; Chemistry;

    Abstract : Galectins are cytosolic protein family involved in several biological functions such as cell differentiation, cell migration and apoptosis amongst many others. Their presence is also substantial in diseases including acute inflammation, fibrosis, allergies, and cancer. READ MORE

  2. 2. Synthesis of fluorescent carbohydrate coumarin hybrids via a three-component reaction : nanomolar galectin-3 inhibitor

    University essay from Lunds universitet/Kemiska institutionen

    Author : Shaun Hoang; [2013]
    Keywords : Organisk kemi; Chemistry;

    Abstract : Galectins play an important role in inflammation, immunity, cancer progression and are potential targets for novel anti-cancer and anti-inflammatory compounds. Coumarin thiodigalacoside hydrid had proved to be potent, nanomolar, and selective inhibitor of galectin-3. READ MORE

  3. 3. An approach to diketone-galectin-3 inhibitor

    University essay from Lunds universitet/Kemiska institutionen

    Author : Shaun Hoang; [2011]
    Keywords : Organisk kemi; Chemistry;

    Abstract : In many biological mechanisms galectins play important roles. The galectins are important in inflammation, immunologic response and cancer. A key function of galectins is cross-linking of their glycoprotein ligands which are connected with the biological activities. Carbohydrate recognition domains (CRD) are responsible for the cross-linking. READ MORE