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1. 1. Evaluation of Microsatellite Instability Analysis as a Diagnostic Tool to Identify Lynch Syndrome in Endometrial Cancer Patients

   University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsa

   Author : Monica Bergfors; [2014]
   Keywords : HNPCC; Hereditary; MSI; Endometrium; Tumour;

   Abstract : Hereditary endometrial cancer (EC) is a Lynch syndrome (LS) related cancer variant and 2-10% of all EC are hereditary. The aim of this study was to develop a method for analysis of microsatellite instability (MSI) as such analysis would assist in identifying potential LS patients with EC at an early state of their disease, before a possible second cancer is developed in another organ. READ MORE