Essays about: "MCF7"

Found 5 essays containing the word MCF7.

  1. 1. Buffer modification: A case study with polystyrene beads, DU145-, and MCF7 cell lines

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Olivia Hansson Rengbrandt; [2023]
    Keywords : Technology and Engineering;

    Abstract : Separation of cancer cells gives advantages in understanding the disease, guiding treatment decisions, and facilitating drug development. Overall, separation plays an important role in biological research. Acoustophoresis is a technique that utilizes acoustic waves to separate particles and cells suspended in a buffer medium. READ MORE

  2. 2. Expanding the application of a novel proteomics tool for drug target and mechanism identification

    University essay from Uppsala universitet/Analytisk kemi

    Author : Linnéa Yuan Andersson; [2022]
    Keywords : ;

    Abstract : In drug discovery and development, characterization of the drug targets and mechanisms of action is an essential step. ProTargetMiner is a publicly available proteome signature library of anticancer molecules and its automated bioinformatics platform can be used for drug target and mechanism deconvolution. READ MORE

  3. 3. Determining the Acoustic Mobility of Breast Cancer Cells

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Simon Olsson; [2022]
    Keywords : Technology and Engineering;

    Abstract : Breast cancer is one of the most common forms of cancer detected in women. Its heterogeneity and large mutational landscape requires treatment strategies which varies between patients. Triple negative breast cancer (TNBC) is a particularly aggressive subtype which 12-17 \% of breast cancer patient develop. READ MORE

  4. 4. ProTargetMiner one step further : Deep comparative proteomics of Dying vs. Surviving cancer cells treated with anticancer compounds

    University essay from Uppsala universitet/Analytisk kemi

    Author : Albin Lundin; [2022]
    Keywords : Cancer; Surviving VS Dying; Proteomics; Comparative Proteomics; RKO; A549; MCF7; drug discovery; life; death; life and death decisions; target ranking; OPLS-DA; drug targets; novel anticancer agents;

    Abstract : Cancer is a leading cause of mortality worldwide, responsible for nearly one in six deaths. Thus, there is a need for a greater understanding of cancer for the development of novel therapeutics. This master thesis project aims to compare the proteome signatures between dying and surviving cancer cells treated with diverse anticancer drugs. READ MORE

  5. 5. Characterizing substances into pharmacological classes using theirmorphological and metabolic profiles

    University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Author : Emma Nygård; [2015]
    Keywords : MCF7-cells; Cytotoxicity; Human; Breast cancer; Phase contrast microscopy; Mass spectrometry;

    Abstract : Treatment of cancers has been improved and new findings in research communities areconstantly found, but there are still many questions about how to treat these complex diseases.One way to treat cancer is to expose cancer cells to drugs that kill the cancer cells to a largerextent than the normal cell from the same as well as other tissue types. READ MORE