Essays about: "Mutation analysis"

Showing result 16 - 20 of 81 essays containing the words Mutation analysis.

  1. 16. Beyond high mutation highrecombination limit in statisticalgenetics

    University essay from KTH/Fysik

    Author : Luc Zorrilla; [2021]
    Keywords : Statistical Genetics; Population genetics; Statistical physics; Linkage Equilibrium;

    Abstract : One considers the bi-allelic model in population genetics which describes a population of genomes evolving under the processes of selection, mutation, recombination and drift. A focus is made on the Quasi-Linkage Equilibrium (QLE) phase with recent derivations from Neher and Shraiman, which exists for fast recombinations compared to selection strength and whose dynamics is greatly simplified compared to the general case. READ MORE

  3. 17. Segmentation and Prediction of Mutation Status of Malignant Melanoma Whole-slide Images using Deep Learning

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Elin Johansson; Fanny Månefjord; [2021]
    Keywords : deep learning; image analysis; malignant melanoma; tissue segmentation; mutation classification; Inception v3; Technology and Engineering;

    Abstract : Malignant melanoma is an aggressive type of skin cancer. Gene mutations can make the disease progress faster, but specialised treatment exists. Today, gene mutations are detected with DNA-analysis which is costly and time-consuming. READ MORE

  4. 18. Model Coverage vs System-under-test Coverage in Model-based testing : Using Edge-pair coverage, Edge coverage, Node coverage and Mutation analysis

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : George Rezkalla; [2021]
    Keywords : model-based testing; system-under-test; edge-pair coverage; edge coverage; node coverage; black-box testing; white-box testing; mutation analysis; test suite effectiveness; modellbaserad testning; system-under-test; kantparstäckning; kant-täckning; nodtäckning; black-box-testning; white-box-testning; mutationsanalys; testsvitseffektivitet;

    Abstract : Model-based testing (MBT) is a black-box software testing technique that focuses on specification of the system-under-test (SUT) and/or its environment. It uses models to automatically generate a large number of tests. READ MORE

  5. 19. Non-coding constraint mutations impact the gene regulatory system in osteosarcoma

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Raphaela Pensch; [2021]
    Keywords : cancer; osteosarcoma; cancer genomics; evolutionary constraint; non-coding mutations; gene regulation;

    Abstract : The non-coding space makes up around 98 % of the genome, but cancer-driving mutations have so far mostly been discovered in protein-coding regions. The majority of somatic non-coding mutations are neutral passenger mutations and identifying non-coding mutations with driving roles in cancer poses a challenge. READ MORE

  6. 20. Development and validation of a novel quantitative PCR analysis method for HIV-1

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Josefine Sundgren; [2020]
    Keywords : HIV-1; qPCR; Octapharma; Taqman; applied biochemistry; tillämpad biokemi; Technology and Engineering;

    Abstract : The major problem when developing primers and probe sets for detection of HIV-1 is its high genetic variability and strong ability to mutate. HIV-1 is divided into four groups, M, N, O, P based on genetic similarities, and there are more than 70 different circulating recombinant forms. READ MORE