Essays about: "Mutation analysis"

Showing result 11 - 15 of 81 essays containing the words Mutation analysis.

  1. 11. Identification of de novo Transcription Factor Binding Motifs Created by Cancer-related Mutations

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Siqi Li; [2022]
    Keywords : transcription factor binding motifs; funMotifs; PCAWG; mutations; de novo motifs;

    Abstract : In many countries, cancer is one of the biggest threats for citizens’ health, especially among aged people. Genomic mutations play a crucial role in cancer cell development. In previous decades, cancer research has been mainly focused on mutations in coding regions. READ MORE

  3. 12. Characterization of a novel EPHB2 R155C mutant with respect to its proteolytic cleavage by TF/FVIIa

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Ece Akcan; [2021]
    Keywords : cancer; colorectal cancer; CRC; ephrin receptor; EPHB2; tissue factor; TF; TF FVIIa; cleavage; cell repulsion;

    Abstract : EPHB2, an ephrin receptor (EPH) from receptor tyrosine kinase (RTK) family, is one of the substrates for tissue factor (TF) - coagulation factor VIIa (FVIIa) complex and it is cleaved in its ectodomain. EPHB2 cleavage is important for ephrin receptor (EPH) - ephrin ligand (EFN) signaling and cell repulsion. READ MORE

  4. 13. Development of a novel quantitative PCR analysis method for HIV-1

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Anna-Malin Hallberg; [2021]
    Keywords : HIV; PCR; primers; probes; virus; detection; blood plasma; pathogen; biological pharmaceutical; protein-based pharmaceutical; genotype; subtype; RT qPCR; extraction; TaqMa; RNA virus; cross-dimer; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering; Chemistry;

    Abstract : Biological pharmaceuticals are the answer to many severe diseases of today’s society. Some of these are protein-based drugs and can be produced from human blood plasma. In order to guarantee the safety of patients, absence of any pathogens needs to be ensured. READ MORE

  5. 14. Relation between αs1-casein, proteolytic activity and composition of milk from Swedish goats

    University essay from SLU/Department of Molecular Sciences

    Author : Emma Larsson; [2021]
    Keywords : swedish goat milk; αs1-casein; total proteolysis; plasmin; plasminogen; spectrophotometry;

    Abstract : In the recent decade, locally produced food has gained in interest among Swedish consumers. Consumer values for buying local food has to do with concerns about diversity, purity and authenticity of food as well as a desire to support rural areas. One type of product that has gained in interest is locally produced goat cheese. READ MORE

  6. 15. A mixed clinicopathological and molecular proxy of homologous recombination deficiency in triple negative breast cancer

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Elise Walford; [2021]
    Keywords : Biology and Life Sciences;

    Abstract : Clinical models are increasingly employed in medical science as either diagnostic or prognostic aids. Machine-learning methods are able to draw links in large data that can be used to predict patient risk and allow more informed decisions regarding treatment and medication intervention. READ MORE