Essays about: "UPLC-MS MS"

Showing result 6 - 10 of 25 essays containing the words UPLC-MS MS.

  1. 6. Using metabolic profiles to screen for novel compounds in deep-sea sponges

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Samira Hilowle; [2022]
    Keywords : Metabolomics; Deep-sea sponges;

    Abstract : The chemical diversity of the phylum Porifera have provided marine natural products (MNPs) such as alkaloids, terpenoids and peptides with ranging biological activity. Every two days a novel compound deriving from sponges are discovered. READ MORE

  2. 7. Method development for the analysis of PFAS and neutral precursors in active and passive air samplers

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Pascal Camoiras González; [2019]
    Keywords : ;

    Abstract : Poly- and perfluoroalkyl substances (PFAS) are a chemical class of global concern because of their persistence, toxicity and widespread presence in the environment. This work aimed to develop a robust and reliable method to analyse perfluorohexane sulfonic acid (PFHxS), perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS), as well as the neutral volatile PFOS precursors, namely perfluorooctane sulfonamides and perfluorooctane sulfonamidoethanols (FOSAs/FOSEs). READ MORE

  3. 8. Immunoassays or LC-MS/MS? : A Comparison Revealing the Properties of Modern Methods for Insulin, Pro-insulin, C-peptide and Glucagon Quantification

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Ruta Upite; Susanna Wärmegård; Casper Tiger; Anna Ivert Nordén; Temis Martinez; Viktor Umenius; [2019]
    Keywords : Biomarker quantification; insulin; pro-insulin; c-peptide; glucagons; immunoassays; LC-MS MS;

    Abstract : The purpose of this report is to compare seven different methods for biomarker detection and quantification based on previously published papers. The methods investigated are ELISA, LC-MS/MS, UPLC-MS/MS, LC-IM/MS, IA-LC-MS/MS, MSIA-HR/AM, HTRF and AlphaLISA ® . READ MORE

  4. 9. Oligonucleotide analysis with 2D-LC-MS using mixed mode column

    University essay from Uppsala universitet/Analytisk farmaceutisk kemi

    Author : Esther Goldberg; [2019]
    Keywords : mass spectrometry; 2D-LC-MS; mixed mode column; oligonuecleotide;

    Abstract : In this project method development for analysis and characterization of an oligonucleotide sample containing two major impurities was done. For this purpose UPLC was used with a RP-WAX mixed mode column with UV and/or MS detection. READ MORE

  5. 10. Occurrence and fate of organic micropollutants (OMPs) in Lake Mälaren

    University essay from SLU/Dept. of Aquatic Sciences and Assessment

    Author : Anna-Lena Rehrl; [2019]
    Keywords : multi-residue method; UPLC-MS MS; SPE; organic micropollutants; surface water;

    Abstract : The main objective of this study is to investigate the occurrence and fate of organic micropollutants (OMPs) in surface water in Lake Mälaren over one year, including their seasonal variations, correlations between compounds, spatial and vertical distribution. The water samples were enriched with solid phase extraction (SPE) and subsequently analyzed by ultra-high pressure liq-uid chromatography tandem mass spectrometry (UPLC-MS/MS). READ MORE