Essays about: "drug discovery process"

Showing result 11 - 15 of 23 essays containing the words drug discovery process.

  1. 11. Molecular Optimization Using Graph-to-Graph Translation

    University essay from Umeå universitet/Institutionen för matematik och matematisk statistik

    Author : Emil Sandström; [2020]
    Keywords : Machine learning; Deep learning; Molecular Optimization; Transformer; Seq2seq; Graph-to-Graph Translation Ac;

    Abstract : Drug development is a protracted and expensive process. One of the main challenges indrug discovery is to find molecules with desirable properties. Molecular optimization is thetask of optimizing precursor molecules by affording them with desirable properties. READ MORE

  2. 12. Advantages of Live-Cell Imaging, its Time Series Data Analysis and Automation in In-Vitro Toxicity Assays during Drug Discovery and Development

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Aishvarya Tandon; [2019]
    Keywords : live-cell imaging; Cell Painting; morphological profiling; drug discovery;

    Abstract : Live cell imaging has not been an active method of analysis during the drug discovery and development phase due to several limitations. This does not change the fact that it along with its time series data analysis describes an undergoing process better than a conventional study with fixed time points. READ MORE

  3. 13. Drug Discovery and Development: Does the maturity of biotech companies affect their stock return volatility?

    University essay from Lunds universitet/Nationalekonomiska institutionen

    Author : Hanna Brännström; [2018]
    Keywords : Stock return volatility; biotech industry; clinical trials; R D; panel data; Business and Economics;

    Abstract : Stock return volatility is very high in the biotech industry opposed to other industries and there is limited explanation as to why. Biotech companies invest large amounts of money on research and development to move drugs forward in the clinical trial phases, to get market approval by the regulatory agency FDA. READ MORE

  4. 14. Classification of High Content Screening Data by Deep Convolutional Neural Networks

    University essay from Uppsala universitet/Institutionen för informationsteknologi

    Author : Karl-Johan Leuchowius; [2017]
    Keywords : ;

    Abstract : In drug discovery, high content screening (HCS) is an imaging-based method forcell-based screening of large libraries of drug compounds. HCS generates enormous amounts of images that need to be analysed and quantified by automated image analysis. READ MORE

  5. 15. A Process and Enterprise Maturity Model (PEMM) Analysis of the Hampered Big Pharma Drug Discovery Process

    University essay from Blekinge Tekniska Högskola/Institutionen för industriell ekonomi

    Author : Andreas Persson; Fredrik Jeppsson; [2017]
    Keywords : ;

    Abstract : The big pharma drug discovery process is currently hampered by long lead times, high costs, and fre-quent failures. On the other hand the general view is that many small pharmaceutical and biotech com-panies are more successful in terms of preclinical drug project transitions, and many small companies and/or their projects are bought by big pharma. READ MORE