Essays about: "endothelial cell ELISA"

Found 2 essays containing the words endothelial cell ELISA.

1. 1. Design, production and in vitro evaluation of brain shuttle scFc-scFv8D3 affinity-mutants

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Jonathan Efverström; [2023]
   Keywords : Blood-brain barrier; In-Cell BBB-trans assay; mTfR1; Transferrin receptor; scFc-scFv8D3; Blod-hjärn barriären; mTfR1; Transferrin receptorn; scFc-scFv8D3;

   Abstract : The blood brain barrier (BBB) is a challenge when developing monoclonal antibodies for neurological diseases as antibodies do not cross the BBB making brain distribution challenging. An antibody construct which binds mTfR1 to pass the BBB, scFc-scFv8D3, have previously been developed. READ MORE

3. 2. IL-17A induced response and synergy with otherproinflammatory cytokines in human endothelial cells

   University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

   Author : Julia Salin; [2021]
   Keywords : cDNA; complementary DNA CVD; cardiovascular disease CXCL1; C-X-C motif ligand-1 EC; endothelial cell ELISA; Enzyme-Linked Immunosorbent Assay HUVECs; human umbilical cord endothelial cells sIL-6R; soluble interleukin 6 receptor IL; interleukin NF-𝜅B; nuclear factor 𝜅B qPCR; quantitative polymerase chain reaction TNF; tumour necrosis factor VSMC; vascular smooth muscle cell;

   Abstract : Cardiovascular diseases are a broad group of diseases, such as heart attack and heart failureaffecting the cardiovascular system. The primary cause of cardiovascular diseases isatherosclerosis, and its progression is brought about by oxidative stress and a complex chronicinflammation reaction cascade. READ MORE