Essays about: "gene therapy"

Showing result 16 - 20 of 52 essays containing the words gene therapy.

  1. 16. Deciphering mechanisms underlying tumor heterogeneity using Multi-Omics approaches

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Joonas Avik; [2020]
    Keywords : Cancer; intratumor heterogeneity; linear model; gene expression; shrinkage;

    Abstract : Cancer is a complex disease and presents one of the greatest challenges in modern medicine. Despite remarkable advances in treatment of several cancer types, relapse and resistance to therapy remain recurring outcomes in patients, which underscores a need for personalized treatment approaches. READ MORE

  3. 17. Intratumoral heterogeneity in early breast cancer

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : MARIA STOGIANNITSI; [2020]
    Keywords : breast cancer; RNAscope technique; heterogeneity of BC; RNA in situ hybridization;

    Abstract : The use of adjuvant The use of adjuvant polychemotherapy (ACT) confers unequivocal benefits in terms of relapse free (RFS) and overall survival (OS) after resection of early breast cancer (BC). Although the magnitude of benefit is the same regardless of clinicopathological factors such as ER expression or nodal stage, it is clear that a substantial proportion of patients will eventually relapse and succumb to the disease. READ MORE

  4. 18. Preimplantation genetic diagnosis and therapy in humans- Opportunities and risks

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Rickard Hedberg; [2020]
    Keywords : Preimplantation genetic diagnosis; CRISPR-Cas systems; gene editing; germline; genome; ethics; autonomy; beneficence; risks.;

    Abstract : IntroductionPreimplantation Genetic Diagnosis (PGD) was developed in the 1990s and has been used since to diagnose and discard embryos with genetic conditions or chromosomal abnormalities. CRISPR-Cas9 was discovered in 2012 and has been used in research, but has not become clinical practice on humans yet. READ MORE

  5. 19. Gene therapy treatment for Parkinson’s disease

    University essay from Lunds universitet/Kemiska institutionen

    Author : Sofie Andresen; [2019]
    Keywords : Parkinson s disease; Gene therapy; Tyrosine hydroxylase; Biochemistry; Chemistry;

    Abstract : Parkinson’s disease (PD) is the most common neurodegenerative disorder after Alzheimer’s disease and today more than 6 million people are living with PD world-wide (2018). PD is characterized by muscle stiffness, shaking at rest, and postural imbalance. READ MORE

  6. 20. Quantifying Differences in Gene Networks via Graph Curvature

    University essay from KTH/Optimeringslära och systemteori

    Author : Viktor Sundström; [2019]
    Keywords : ;

    Abstract : Fast improvements of technologies for the acquirement of large genomic data through single cell RNA-sequencing have led to a need for new mathematical methods for the analysis of such data. One approach of representing this data that has emerged over the last couple of decades is through graph representations, i.e. READ MORE