Essays about: "tonicity adjusting agents"

Found 1 essay containing the words tonicity adjusting agents.

  1. 1. Study of surfactant-preservative and protein-preservative interactions in multi-dose injectable formulation

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Javier Lagares Martín; [2023]
    Keywords : Phenol; polysorbate 80; cloud point; somatropin; aggregation; titration; light scattering; salt; surfactant; preservative; protein; tonicity adjusting agents; multi-dose injectable formulation; pharmaceutical technology; Technology and Engineering;

    Abstract : Multidose injectable formulations require a preservative such as phenol to ensure sterility and protection against microbial contamination during clinical use. However, it is known that the interaction between these components and non-ionic surfactants such as polysorbate 80, also found in this type of formulations, present incompatibilities, which can lead to decreases in the efficacy of the product. READ MORE