Essays about: "Affibody"
Showing result 21 - 23 of 23 essays containing the word Affibody.
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21. Evaluation of accuracy in simultaneous dual-radionuclide activity quantification in preclinical instruments – scintillation counter, digital autoradiography and micro-SPECT/CT
University essay from Lunds universitet/SjukhusfysikerutbildningenAbstract : Introduction: The development and optimization of methods for multi-radionuclide measurements in preclinical in vivo and ex vivo SPECT imaging could potentially improve studies in which more than one pharmaceutical is being investigated. The aim of this study is to quantitatively compare and evaluate different methods for these types of measurements using three different modalities – a small animal SPECT/CT, a scintillation counter and a digital autoradiography instrument. READ MORE
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22. Process development for the control of solubility of Affibody® molecules
University essay from Institutionen för biologisk grundutbildningAbstract : In this study the aim was to optimize the production of the Affibody fusion-protein Z03358- ABD094-(S4G)3-IL2 with regard to the amount of soluble protein produced. However, problems with reproducibility with this protein and the chosen expression system were encountered. READ MORE
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23. High-throughput Fed-batch Production of Affibody® molecules in a novel Multi-fermentor system
University essay from Institutionen för fysik, kemi och biologiAbstract : The present Master thesis describes the development and optimization of a fed-batch process for production of recombinant proteins in Escherichia coli BL21(DE3) in a multi-fermentor system. The system consists of six 1-liter fermentors, capable of producing 500-1500 μg/mL with present protocol. READ MORE