Essays about: "EAE MS"

Found 1 essay containing the words EAE MS.

  1. 1. Suppressive DNA vaccination in Experimental Autoimmune Encephalomyelitis and how it affects gene expression of inflammatory mediators

    University essay from Institutionen för medicinsk biokemi och mikrobiologi

    Author : Charlotta Jakobsson; [2007]
    Keywords : EAE MS; IL-17; IL-17 producing T-cells; autoimmunity; autoimmune T-cell responses; interfering RNA;

    Abstract : Vaccination with DNA encoding the encephalitogenic autoantigen myelin oligodendrocyte glycoprotein (MOG), pMOG91-108, induce a protective immunity against experimental autoimmune encephalomyelitis (EAE), an animal model of human multiple sclerosis. By injection of a DNA vaccine that contains a DNA region encoding short interfering RNA specific for IFNβ (pMOG-IFNβ) the protective effect of the DNA vaccination is totally inhibited. READ MORE