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Found 2 essays matching the above criteria.

1. 1. The influence of dissolution medium on in vitro dissolution profiles for pulmonary drug delivery

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Venus Zafranian; [2021]
   Keywords : Inhalation; in vitro dissolution; budesonide; fluticasone propionate; modified andersen cascade impactor; pulmonary drug delivery; dissolution profiles; dissolution medium;

   Abstract : Today, orally inhaled drugs found on the market suffer from variable and discontinuous pulmonary drug release which lowers efficacy and patience compliance. This is usually a consequence of the poor understanding of the interaction and dissolution behavior of drug particles in the lung environment. READ MORE

3. 2. Characterization of the effect of the membrane on in vitro dissolution profiles for pulmonary drug delivery

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Maral Simonides; [2021]
   Keywords : Oral inhalation; in vitro dissolution; Budesonide; Fluticasone propionate; Transwell;

   Abstract : It has always been a challenge to imitate the lung environment, therefore there is a constant development of standardized in vitro dissolution methods for inhaled products. Dissolution in vitro has been considered as an important parameter, because low solubility determines the bioavailability of inhaled drugs. READ MORE