Essays about: "GLP-1R"

Found 2 essays containing the word GLP-1R.

1. 1. A porcine type 1 Diabetes Mellitus model, for non-invasive in vivo imaging of the glucagon-like peptide-1 receptor in the pancreas, using [68Ga]Ga-DO3A-VS-Cys40-conjugated synthetic exendin-4 in PET-CT

   University essay from SLU/Dept. of Clinical Sciences

   Author : Susanne Andréasson; [2014]
   Keywords : Exendin-4; GLP-1R; pig; beta cell imaging; beta cell mass; Exendin-4; gris; betacellsmassan; PET-CT;

   Abstract : Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. READ MORE

3. 2. Effect of GLP-1R Knockout on stroke outcome

   University essay from KTH/Skolan för teknik och hälsa (STH)

   Author : Alexandra Voinea; [2014]
   Keywords : Technology;

   Abstract : Stroke is the leading cause of disability in adults in westernized societies and it has an important impact on health and economy. Comorbid health conditions such as hypertension, inactive lifestyle, smoking, obesity and diabetes considerably increase the risk of stroke. READ MORE