Essays about: "High resolution mass spectrometry"

Showing result 1 - 5 of 18 essays containing the words High resolution mass spectrometry.

  1. 1. Synthesis of aromatic thiol ligands for the formation of thermoelectric materials

    University essay from KTH/Kemi

    Author : Clément Bouchut; [2024]
    Keywords : ligand; organic chemistry; organic synthesis; thermoelectric materials; thiol; ligand; organisk kemi; organisk syntes; termoelektriska material; tiol;

    Abstract : I detta arbete så har en uppsättning aromatiska ditiol-ligander framställts (3,5-dimerkaptobensoesyra I, methyl-3,5-dimerkaptobensoat II, 3,5-dimerkaptotoluen III, 4,6-dimerkaptoisoftalaldehyde IV). En trestegssyntes innehållande Newman-Kwart omlagring som nyckelsteg användes för framställning av föreningarna I-III medan förening IV togs fram via en annan syntesväg. READ MORE

  3. 2. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    University essay from Uppsala universitet/Analytisk kemi

    Author : Maryam Dost; [2024]
    Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

  4. 3. Identification of photodegradation products from commonenvironmental pollutants using gas chromatography coupled withhigh resolution mass spectrometry

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Vanessa Cajes; [2022]
    Keywords : Photodegradation; Organic contaminants; High resolution mass spectrometry; Identification; Spectral library;

    Abstract : Photodegradation is a major degradation mechanism for many environmental contaminants, both in indoor environments as well as in outdoor environments, and many of the contaminants are persistent and toxic. However, there is a lack of knowledge about the exact degradation process for many of them. READ MORE

  5. 4. Building an in-house spectral library using GCorbitrap HRMS

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Elias Kolsmyr; [2022]
    Keywords : Environmental contaminants; Plastic additives; Gas chromatography; High resolution mass spectrometry; Spectral library; MS-DIAL;

    Abstract : There are a great variety of environmentals contaminants, a lot of which are understudied asit is today. The aim of this study was to develop an in-house high-resolution spectral librarycontaining environmental contaminants, with focus on plastic additives. The spectral librarywould then be used to perform suspect screening on real sample extracts. READ MORE

  6. 5. Non-target screening of sediment samples fromthe Canadian Arctic: comparing two different gas chromatography – high resolution mass spectrometry (GC-HRMS) techniques

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Mathilda Timner; [2022]
    Keywords : Arctic marine sediment ׀ GC×GC-HR-ToF-MS ׀ GC-Orbitrap-MS ׀ Identification ׀ Non-target screening ׀ Organic pollutants;

    Abstract : Since the late 18th century, chemicals have been industrially produced, and used by consumers. Today, the number of registered chemicals are over 150 000 in North America and Europe alone, and the number is predicted to increase. READ MORE