Essays about: "biological drugs"

Showing result 6 - 10 of 44 essays containing the words biological drugs.

  1. 6. Investigation of Chromatin Organization and mRNA Expression in Drug Treated Human Erythroleukemia Cells

    University essay from KTH/Proteinvetenskap

    Author : Anam Minhas; [2022]
    Keywords : Erythroleukemia cells; mRNA-seq; ATAC-seq; Doxorubicin; Vinblastine; Erytroleukemiceller; mRNA-expression; kromatin; Doxorubicin; Vinblastine;

    Abstract : Syftet med detta projekt var att undersöka hur vanligt använda cancerläkemedel påverkar mRNA-uttryck och kromatinorganisation i humana erytroleukemiceller. Som modell användes K562-celler från en patient i blastocystkris (2), för att utvärdera leukemicellernas svar på cancerläkemedel vinblastin och doxorubicin. READ MORE

  3. 7. Coacervates as a subcutaneous drug delivery system

    University essay from Uppsala universitet/Institutionen för läkemedelskemi

    Author : Dania Elkhalifa; [2022]
    Keywords : ;

    Abstract : Subcutaneous administration of biological drugs has become highly attractive as it offers the possibility for patient self-administration. Coacervates as a subcutaneous drug delivery system provide a way to decrease injection volumes thereby reducing the risk of injection site pain. READ MORE

  4. 8. Development of Microfluidic 3D Cell Culture with a Nanocellulose-Based Scaffold for Spheroid Formation as a Potential Tool for Drug Screening

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Sara Payande; [2022]
    Keywords : 3D cell culture; Scaffold; Microfluidics; Layer-by-Layer; Cellulose Nanofibrils; Spheroids; HepG2; 3D cellodling; Matris; Mikrofluidik; Layer-by-Layer; Cellulosa Nanofibriller; Sfäroider; HepG2;

    Abstract : Abstract  Lack of clinical relevance is assumed to be the main reason behind the high failure rate of medical drugs in the very initial phases of clinical trials. Clinical relevance is difficult to achieve with current tools as they lack the biological and physiological cues found in vivo. READ MORE

  5. 9. Quality and Regulatory Issues Related to Continuous Manufacturing of Biologics

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Sorosh Ziarati; [2022]
    Keywords : Continuous Manufacturing; Regulation; Continuous freeze drying; Biopharmaceutical; Trastuzumab; Pharmaceutical Technology; Technology and Engineering;

    Abstract : Introduction: Continuous Manufacturing involves the continuous feeding of input materials into the transformation of in-process materials within, and the concomitant removal of output materials from a manufacturing process based on ICH guideline. In these systems, all the processes from raw material to final finished product would be continuously produced. READ MORE

  6. 10. Monitoring illicit drugs of abuse in wastewater from Umeå, Örebro, Örebro University and Örebro University Hospital

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Tove Slettvoll; [2022]
    Keywords : ;

    Abstract : Illicit drugs constitute a class of contaminants whose emissions to the environment has drawn attention due their potent pharmacological and biological activities. The monitoring of illicit drugs in wastewater and surface waters provides a powerful tool to investigate the presence, trends and to estimate the consumption of these psychoactive substances at the community level. READ MORE