Essays about: "3D cellodling"

Found 2 essays containing the words 3D cellodling.

1. 1. Development of Microfluidic 3D Cell Culture with a Nanocellulose-Based Scaffold for Spheroid Formation as a Potential Tool for Drug Screening

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Sara Payande; [2022]
   Keywords : 3D cell culture; Scaffold; Microfluidics; Layer-by-Layer; Cellulose Nanofibrils; Spheroids; HepG2; 3D cellodling; Matris; Mikrofluidik; Layer-by-Layer; Cellulosa Nanofibriller; Sfäroider; HepG2;

   Abstract : Abstract  Lack of clinical relevance is assumed to be the main reason behind the high failure rate of medical drugs in the very initial phases of clinical trials. Clinical relevance is difficult to achieve with current tools as they lack the biological and physiological cues found in vivo. READ MORE

3. 2. How Topography Influences the Fate of Human Neural Progenitor Cells

   University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

   Author : Jacob Karlström; [2020]
   Keywords : biomaterials; cell culture; electrospinning; nanofibers; 3d; neural progenitor cells; in vitro models; nanotopography; blebbistatin; mechanotransduction; nucleus analysis; immunocytochemistry; differentiation; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering;

   Abstract : Novel biomimetic three-dimensional scaffolds have emerged over the last decades, and are promising for applications in regenerative therapies, as well as in in vitro disease modelling and drug testing. Thanks to their added dimension, these scaffolds are able to more accurately mimic the topography of native cellular microenvironments compared to traditionally used two-dimensional culture substrates. READ MORE