Essays about: "calcium-dependency"

Found 1 essay containing the word calcium-dependency.

  1. 1. Characterization of novel ZCa-based variants to investigate calcium dependent target interaction

    University essay from KTH/Proteinvetenskap

    Author : Gabriella Rossi; [2021]
    Keywords : ZCa; IgE; IL-23; recycling antibody; calcium-dependency;

    Abstract : ZCa is an engineered three-helical affinity protein that through replacement of the loop between helix two and three with an EF-hand motif has a calcium-dependent binding to its target. By using the difference of calcium concentration in the plasma and the cell along with the favorable properties of ZCa, the interest in creating therapeutics toward different diseases based on the ZCa scaffold has come about. READ MORE