Essays about: "in situ hybridization"
Showing result 6 - 10 of 18 essays containing the words in situ hybridization.
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6. Intratumoral heterogeneity in early breast cancer
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : The use of adjuvant The use of adjuvant polychemotherapy (ACT) confers unequivocal benefits in terms of relapse free (RFS) and overall survival (OS) after resection of early breast cancer (BC). Although the magnitude of benefit is the same regardless of clinicopathological factors such as ER expression or nodal stage, it is clear that a substantial proportion of patients will eventually relapse and succumb to the disease. READ MORE
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7. Characterisation of Transcription Factor Regulation During the Development of Zebrafish Craniofacial Structures
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : The appearance of jaws approximately 420 million years ago was a major event in vertebrate evolution. This new structure allowed gnathostomes to take on roles as active predators and increase their energy intake, facilitating their success as a group. READ MORE
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8. Optimization of PCR protocols used for genotyping transgenic mice & Evaluation of a method for co-detecting mRNA and protein
University essay from Uppsala universitet/Jämförande fysiologiAbstract : The aim of the current study was divided into two separate goals, (i) optimization of a number of PCR-based protocols employed for genotyping transgenic mouse lines and (ii) evaluating a protocol for co-detection of mRNA and its correlated protein in the mouse midbrain. The optimization was performed on PCR protocols for genotyping the following transgenic mouse lines; Dat-Cre, Vglut2-Lox, Vglut2-Cre and Vmat2-Lox. READ MORE
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9. Can massive parallel sequencing replace fluorescent in situ hybridization for detection of fusion genes in patients with non-small cell lung cancer?
University essay from Örebro universitet/Institutionen för hälsovetenskaperAbstract : Abstract Today the golden standard method to find fusion genes is with fluorescent in situ hybridization. Massive parallel sequencing is a method that can analyze several genes and samples at the same time at a lower cost. READ MORE
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10. Develop an automated staining protocol for ProxHCR
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Proximity hybridization chain reaction (ProxHCR) is a novel in situ hybridization technique capable of detecting protein-protein interactions and post-translational modifications, having the potential to be a diagnostic and prognostic tool in clinical practice. As molecular pathology is becoming an integrated part of clinical evaluations, most staining procedures done today are automated. READ MORE
