Essays about: "neutrophil Elastase"

Found 3 essays containing the words neutrophil Elastase.

  1. 1. Visualizing osteonecrosis of jaws through neutrophil elastase : [11C]NES novel PET tracer

    University essay from Uppsala universitet/Institutionen för läkemedelskemi

    Author : Amanda Dannberg; Theodora Martinez; [2023]
    Keywords : [11C]NES; HNC; MRONJ; neutrophil granulocytes; ORN; osteonecrosis; PET CT; radiation therapy; [11C]NES; huvud- och halscancer; MRONJ; neutrofila granulocyter; ORN; osteonekros; PET CT; strålbehandling;

    Abstract : Radiation and medical drugs are used to fight head and neck cancer, but unfortunately in some cases these treatments cause development of other diseases and injuries. Osteoradionecrosis (ORN) and medical-related osteonecrosis of the jaw (MRONJ) are dreaded late complications in jaws from radiation therapy and medical drugs and cause great suffering to those affected. READ MORE

  3. 2. Peptide fragment screening towards a new inhibitor of neutrophil elastase

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Tomas Szakacs; [2019]
    Keywords : pharmaceutical technology; läkemedelsteknologi; Chemistry; Technology and Engineering;

    Abstract : The main purpose of this master thesis was to test a novel approach of finding leads for new pharmaceuticals, by using Solid Phase Peptide Synthesis (SPPS) in combination with Weak Affinity Chromatography (WAC). Put in a more concrete way, the objective was to find a lead for a better human neutrophil elastase inhibitor. READ MORE

  4. 3. Enzymatic cleavage of HMGB1

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Merlin Rensing; [2017]
    Keywords : HMGB1; enzymatic cleavage; neutrophil Elastase; cathepsin G; matrix metalloproteinase-3; arthritis;

    Abstract : Alarmins and damage associated molecular pattern (DAMP) are endogenous proteins with distinct and various intracellular roles that when released extracellularly act as startingsignals for inflammatory immune responses. The endogenous protein High mobility group box 1 (HMGB1) acts as a DAMP and has been shown to drive progression of multiple inflammatory and autoimmune diseases. READ MORE