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Found 2 essays matching the above criteria.

1. 1. Design and analysis of pre-clinical experiments using a method combining multiple comparisons and modeling techniques for dose-response studies

   University essay from Göteborgs universitet/Institutionen för matematiska vetenskaper

   Author : Avijit Singh; [2021-04-20]
   Keywords : pharmacodynamic modeling; dose–response relationship; significance level; multiple comparison procedure; optimal design; MCPMod; dose finding study;

   Abstract : Abstract. Identifying and estimating the dose-response relationship between a compound and a pharmacological endpoint of interest is one of the most important and difficult goals in the preclinical stage of pharmaceutical drug development. READ MORE

3. 2. Linking Systems Models of Pharmacology with Behavioural Models of Adherence : A Feasibility Study

   University essay from KTH/Medicinteknik och hälsosystem

   Author : Simon Jenner; Dennis Amphan; [2020]
   Keywords : Pharmacology; Pharmacokinetics; Pharmacodynamics; PKPD-model; Diabetes; Adherence; Modelling; Feasibility; Farmakologi; Farmakokinetic; Farmakodynamik; PKPD-model; Diabetes; ̊Atlydnad; Modellering; Genomf ̈orbarhet;

   Abstract : Pharmacokinetic (PK)- and pharmacodynamic (PD) modeling are useful tools whenassessing treatment effect. A patient’s adherence can potentially be rate-limiting, since it isthe first process in a chain of processes that determines treatment effect. READ MORE