Essays about: "Proteins"

Showing result 21 - 25 of 938 essays containing the word Proteins.

  1. 21. A Machine Learning Approach on Analysis of Emission Spectra for Application in XFEL Experiments

    University essay from Uppsala universitet/Institutionen för fysik och astronomi

    Author : Harald Agelii; [2023]
    Keywords : Structural biology; Machine learning; Neural networks; emission spectrum; XFEL; X-ray free electron laser; SFX; Serial femtosecond X-ray crystallography; Proteins; Diagnostics;

    Abstract : In this thesis we investigate two potential applications of machine learning in the context of X-ray imaging and spectroscopy of biological samples, particularly such using X-ray free electron lasers (XFEL). We first investigate the possibility of using an emission spectrum, recorded from a sample after being probed by an incident X-ray, as a diagnostic tool. READ MORE

  3. 22. Sortase A coupling of the recombinant partial silk proteins 4Rep-Srt and G-/G5-CT to understand the structure of silk fiber

    University essay from KTH/Proteinvetenskap

    Author : Ellen Adlerz; [2023]
    Keywords : 4RepCT; 4Rep-Srt; G- G5-CT; Sortase A coupling; recombinant silk protein; 4RepCT; 4Rep-Srt; G- G5-CT; Sortase A-koppling; rekombinant silkesprotein;

    Abstract : Spindelsilke är ett intressant material på grund av dess biokompatibilitet och därav användning som biomaterial. Det är jämförbart med konstgjorda material när det gäller styrka och elasticitet, och i kombination med biokompatibiliteten, är spindelsilke eftertraktat inom det medicinska området. READ MORE

  4. 23. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design

    University essay from Uppsala universitet/Beräkningsbiologi och bioinformatik

    Author : Linde Brokmar; [2023]
    Keywords : Protein design; de novo design; protein engineering; generative ai; machine learning; peptide binders; AF2; EvoBind; RFdiffusion; ProteinMPNN;

    Abstract : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. READ MORE

  5. 24. Characterization of Antigenic Properties of Two Immunogenic Proteins of Streptococcus pneumoniae 

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Mawj Jasimalsalih; [2023]
    Keywords : Immunogenic Proteins; PrsA; MalX; Membrane Vesicles; Protein Properties; Streptococcus pneumoniae virulence factors;

    Abstract : The bacterium Streptococcus pneumoniae (pneumococcus), is considered to be a leading cause of morbidity and mortality globally, particularly in infants and the elderly. It is one of the most frequent causes of respiratory tract infections, which sporadically have the potential to develop into serious invasive symptoms including sepsis and meningitis. READ MORE

  6. 25. Characterization of Mitilysin Pores by Cryo-electron Microscopy

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Vladimir Novakovic; [2023]
    Keywords : Mitilysin; Mly; Structural Biology; Cryo-EM; pore; toxin; pore forming proteins; pore forming toxins; PFP; PFT;

    Abstract : Pore forming toxins (PFTs) are a large group of proteins found mainly in bacteria with some exceptions found in animals. They bind and form pores in their target membranes and form pores, which leads to cell death. Among these are cholesterol-dependent cytolysins (CDC), which require the presence of cholesterol to bind target membranes. READ MORE