Essays about: "Cell culture"

Showing result 16 - 20 of 119 essays containing the words Cell culture.

  1. 16. Three-Dimensional Cartilage CultureModel – Cell Culture and Analysis ofChondrogenesis

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Mario Zambrana; [2022]
    Keywords : ;

    Abstract : Background: Articular cartilage injuries are a major challenge in orthopedic surgery. Articular cartilage has a low metabolic activity, and it is avascular. Therefore, when injuries occur cartilage has a limited capacity to fully regenerate. READ MORE

  3. 17. Inducing an immunosuppressed phenotype inprimary monocytes through exposure to viralproteins.

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Seat Foung Chiu-Lilja; [2022]
    Keywords : ;

    Abstract : Background. Sepsis has been defined as a hyperactive dysregulated inflammatory response that can lead tohigh fevers, shock and multiple organ failure. However, newer findings indicate that LPS canreprogram monocytes to adopt a suppressed immune response-phenotype leading to increasedsusceptibility and mortality in a secondary infection. READ MORE

  4. 18. Developing and validating assay-ready HEK-Blue CD40L cells : For a more flexible and faster screening of Affibody® molecules

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Erika Könberg; [2022]
    Keywords : cell biology; assay-ready cells; HEK-Blue cells;

    Abstract : Cell assay that evaluates a biologics’ potency and efficacy is an important part in the discovery and development of drug candidates. However, it requires regular maintenance of cell cultures, and the cell assays can only be performed when the cells have reached 70-80% confluency. READ MORE

  5. 19. Different concentrations of GSK3 inhibitor fail to suppress interleukin-6 in stimulated THP-1 macrophage

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Batoul Shunnar; [2022]
    Keywords : ;

    Abstract : Inflammation is a defensive process that allows immune cells to be mobilized to help with infection removal and tissue regeneration. Inflammasomes are multiprotein oligomers in the cytoplasm and components of the innate immune system that have a role in inflammation. READ MORE

  6. 20. Development of Microfluidic 3D Cell Culture with a Nanocellulose-Based Scaffold for Spheroid Formation as a Potential Tool for Drug Screening

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Sara Payande; [2022]
    Keywords : 3D cell culture; Scaffold; Microfluidics; Layer-by-Layer; Cellulose Nanofibrils; Spheroids; HepG2; 3D cellodling; Matris; Mikrofluidik; Layer-by-Layer; Cellulosa Nanofibriller; Sfäroider; HepG2;

    Abstract : Abstract  Lack of clinical relevance is assumed to be the main reason behind the high failure rate of medical drugs in the very initial phases of clinical trials. Clinical relevance is difficult to achieve with current tools as they lack the biological and physiological cues found in vivo. READ MORE