Essays about: "FFPE"

Showing result 1 - 5 of 9 essays containing the word FFPE.

  1. 1. The density of CD163+ macrophages in different subtypes of breast cancer

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Julia Andersson; [2022]
    Keywords : breast cancer; molecular subtypes; macrophages; immunohistochemistry; CD163;

    Abstract : Introduction Breast cancer is the most common cancer among women in Sweden and world-wide. Immunohistochemical (IHC) expression of oestrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and Ki-67 is routinely performed for diagnostic and prognostic purposes. READ MORE

  3. 2. Evaluation of pretreatment methods for formalin-fixed paraffin-embedded extrapulmonary tuberculosis tissue : Improvement of lab developed molecular diagnostics of Mycobacterium-complex

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Anna-Sara Schultz; [2021]
    Keywords : ;

    Abstract : Tuberculosis (TB) disease is a world-wide spread disease caused by Mycobacterium tuberculosis which affects a significant percentage of the world population. The disease is often localized in the lungs, but can further develop and spread to other organs and is then called extrapulmonary TB (EPTB). READ MORE

  4. 3. Detection of artefacts in FFPE-sample sequence data

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Hugo Swenson; [2019]
    Keywords : Cancer; FFPE; Sequence Artefacts; Precision Medicine; Bioinformatics; Program;

    Abstract : Next generation sequencing is increasingly used as a diagnostic tool in the clinical setting. This is driven by the vast increase in molecular targeted therapy, which requires detailed information on what genetic variants are present in patient samples. READ MORE

  5. 4. Unlocking the Proteome of Archival Tissue Collections : Proteomic Analysis of Urinary Bladder Cancer Tissues using Mass Spectrometry-based Proteomics

    University essay from Uppsala universitet/Analytisk kemi

    Author : Aleš Holfeld; [2017]
    Keywords : ;

    Abstract : Formalin-fixed and paraffin-embedded (FFPE) and optimal cutting temperature (OCT)-embedded frozen tissue samples have recently gained interest as they exist in vast repositories worldwide and represent a valuable resource for clinical studies. However, unlocking the proteome of these archival tissues has encountered many challenges. READ MORE

  6. 5. Can massive parallel sequencing replace fluorescent in situ hybridization for detection of fusion genes in patients with non-small cell lung cancer?

    University essay from Örebro universitet/Institutionen för hälsovetenskaper

    Author : Caroline Rolandsson; [2017]
    Keywords : ;

    Abstract : Abstract Today the golden standard method to find fusion genes is with fluorescent in situ hybridization. Massive parallel sequencing is a method that can analyze several genes and samples at the same time at a lower cost. READ MORE