Essays about: "immunohistochemistry"

Showing result 1 - 5 of 79 essays containing the word immunohistochemistry.

  1. 1. Establishment and Characterisation of new Immunoreagents for diagnosis of Ovarian cancer

    University essay from

    Author : Fanny Carlsson; [2023-04-19T12:15:23Z 2023-04-19T12:15:23Z 2022 2023]
    Keywords : ovarian; cancer; monoclonal; antibodies; biomarkers; CARM1; PARPi; EZH2i;

    Abstract : Ovarian cancer is the most lethal of all gynaecological cancers and it is often diagnosedat an advanced stage due to diffuse and only mild symptoms at early stages.Early detection is crucial to increase survival but high-grade serous ovarian cancer(HGSOC) often presents non-specific symptoms, such as loss of appetite, bloating ofabdomen and tiredness. READ MORE

  3. 2. Molecular characterization of vascular malformations using single-cell RNA sequencing and immunohistological analysis

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Amanda Norrén; [2023]
    Keywords : ;

    Abstract : CCM is a human disease in which vascular malformations develop in the central nervous system, predominantly in the brain. The malformations which can measure up to several centimeters in size are dilated and leaky vessels, with unstable cellular junctions and thin vessel walls. READ MORE

  4. 3. Single-cell transcriptomic and antibody-based proteomic analysis of Sertoli cell-specific markers in human testis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Katharina Stanzel; [2023]
    Keywords : ;

    Abstract : The testis is a complex organ responsible for sperm production and hormone synthesis. Spermatogenesis, the process of sperm formation, occurs in the seminiferous tubules and involves the coordinated development of germ cells with the support of Sertoli cells. READ MORE

  5. 4. Influence of Nrf2 Activators and Keap1 Inhibitors on Antioxidative Phenotypes of THP-1-Derived M1 and M2 macrophages: Therapeutic Potential for Systemic Lupus Erythematosus

    University essay from Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Author : Leo Svahn; [2023]
    Keywords : NRF2; KEAP1; THP-1; M1; M2; SLE;

    Abstract : POPULAR SCIENTIFIC SUMMARY Systemic lupus erythematosus (SLE) is not your average disorder. It behaves like a mischievous troublemaker, wreaking havoc throughout the body, causing inflammation that affects multiple organs. READ MORE

  6. 5. Digital Image Analysis using Qupath to determine immune cell content in formalin-fixed, paraffin-embedded murine neuroblastoma tumors

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Anton Bergström Holm; [2023]
    Keywords : Neuroblastoma; Tumor-associated neutrophils TANs ; Digital image analysis; QuPath;

    Abstract : Neuroblastoma (NB), an extracranical solid tumor, is among the most prevalent cancers affecting children, particularly those under the age of five. High-risk NB presents a survival rate just below 50 %. Angiogenesis, a crucial process in NB, is induced by various pro-angiogenic factors. READ MORE