Essays about: "molecular subtypes"

Showing result 1 - 5 of 9 essays containing the words molecular subtypes.

1. 1. Examination of pathway crosstalk and functional modules in papillary thyroid cancer dedifferentiation to anaplastic thyroid cancer

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Maria Panagiota Theodorou; [2023]
   Keywords : ;

   Abstract : Thyroid cancer, comprising well-differentiated follicular and papillary types, alongside less common medullary and anaplastic subtypes with poor prognoses, exhibits specific anaplastic cases resulting from papillary dedifferentiation, lacking precise molecular evidence. Utilizing Metascape, CTpathway and PathwAX II, the study integrates functional modules and pathway crosstalk for dedifferentiation analysis, conducting a comprehensive two-dimensional assessment of toolset’s functionality, compatibility, and interoperability. READ MORE

3. 2. How molecular diagnostics based on gene expressions can improve diagnostics in Sarcoma

   University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

   Author : Emma Friberg; Alma Lennartsson; [2023]
   Keywords : Technology and Engineering;

   Abstract : Sarcoma, a rare and heterogeneous cancer type, present significant diagnostic challenges due to its numerous subtypes. Molecular diagnostics and machine learning models have emerged as promising tools to enhance sarcoma diagnosis. READ MORE

4. 3. The density of CD163+ macrophages in different subtypes of breast cancer

   University essay from Örebro universitet/Institutionen för medicinska vetenskaper

   Author : Julia Andersson; [2022]
   Keywords : breast cancer; molecular subtypes; macrophages; immunohistochemistry; CD163;

   Abstract : Introduction Breast cancer is the most common cancer among women in Sweden and world-wide. Immunohistochemical (IHC) expression of oestrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and Ki-67 is routinely performed for diagnostic and prognostic purposes. READ MORE

5. 4. A mixed clinicopathological and molecular proxy of homologous recombination deficiency in triple negative breast cancer

   University essay from Lunds universitet/Examensarbeten i bioinformatik

   Author : Elise Walford; [2021]
   Keywords : Biology and Life Sciences;

   Abstract : Clinical models are increasingly employed in medical science as either diagnostic or prognostic aids. Machine-learning methods are able to draw links in large data that can be used to predict patient risk and allow more informed decisions regarding treatment and medication intervention. READ MORE

6. 5. Identification of changes in biomarkers relevant for breast cancer biology occurring in a novel 3D-Biosilk model

   University essay from KTH/Proteinvetenskap

   Author : Emmy Ståhl; [2021]
   Keywords : 3D-Biosilk; breast cancer; 3D cell culture; recombinant spider silk; ZO-1; 3D-Biosilk; bröstcancer; 3D cellkultur; rekombinant spindeltråd; ZO-1;

   Abstract : Bröstcancer är den vanligaste formen av cancer som drabbar kvinnor. Det är en heterogen och komplex sjukdom som består av flera undergrupper, var och en med distinkt morfologi och kliniska implikationer [1]. För att modellera och studera cellbiologi, vävnadsmorfologi, molekylära mekanismer och läkemedels effekter används cellkulturer [2]. READ MORE