Essays about: "Gene networks"
Showing result 1 - 5 of 52 essays containing the words Gene networks.
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1. Combining Cell Painting, Gene Expression and Structure-Activity Data for Mechanism of Action Prediction
University essay from Uppsala universitet/Nationellt resurscentrum för biologi och bioteknikAbstract : The rapid progress in high-throughput omics methods and high-resolution morphological profiling, coupled with the significant advances in machine learning (ML) and deep learning (DL), has opened new avenues for tackling the notoriously difficult problem of predicting the Mechanism of Action (MoA) for a drug of clinical interest. Understanding a drug's MoA can enrich our knowledge of its biological activity, shed light on potential side effects, and serve as a predictor of clinical success. READ MORE
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2. Gene Biomarker Identification by Distinguishing Between Small-Cell and Non-Small Cell Lung Cancer Through a Module-Based Approach
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Lung cancer is the leading cause of cancer-related deaths worldwide and is divided into two broad histological types, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Network module-based approach is applied to lung cancer subtypes in order to analyze and compare the results with previous literature and thus discover new genetic biomarkers and/or confirm previously discovered ones. READ MORE
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3. Quantification of DNA Nanoballs Using Image Processing Techniques
University essay from Uppsala universitet/Avdelningen Vi3Abstract : In gene editing, it is important to identify the number of edited and unedited nucleic acids in the development of new therapies and drugs. Countagen is developing a technology for accelerating genomic research and their product is called GeneAbacus. READ MORE
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4. Inferring Gene regulatory networks using Graph Neural Networks
University essay from KTH/GenteknologiAbstract : Inom beräkningsbiologin är det snabbt på väg att bli allt vanligare att ta fram genetiska regleringsnätverk (GRN). På grund av storleken på de undersökta nätverken använder många forskare maskininlärning för att härleda GRN från genuttrycksdata, vanligtvis från RNA-seq. READ MORE
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5. Design and production of adeno-associated virus vectors for imaging mitochondrial networks in the brain
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Mitochondria are dynamic organelles that function in a complex interconnected network within the cell. Neurons are sensitive and highly energy demanding cells in the brain which require a functioning mitochondrial network that is able to provide ATP and modulate calcium. READ MORE