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  1. 1. Optimization of a Methodology for Cell Based Untargeted Metabolomics with UHPLC-Q-ToF-MS

    University essay from Uppsala universitet/Analytisk farmaceutisk kemi

    Author : Jens Westerinen; [2020]
    Keywords : ;

    Abstract : Metabolomics is the study of small molecules (molecular weight < 1500 Da) in a biological system and can provide relevant information about endpoints of biochemical pathways by establishing metabolic profiles for different sample cohorts and comparing these through multivariate data analysis. The aim of this thesis was to establish and test a suitable methodology for cell-based untargeted metabolomics, utilizing UHPLC-MS. READ MORE