Essays about: "Lipid based formulations LBFs"

Found 2 essays containing the words Lipid based formulations LBFs.

  1. 1. In vitro performance prediction of LBFs using lipolysis-permeation assay with the LiDo artificial membrane: Validation and protocol optimization

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Alaa Zangana; [2021]
    Keywords : ;

    Abstract : Lipid-based formulations (LBFs) can be an effective formulation strategy to improve the bioavailability of lipophilic drugs. However, conventional single-compartment in vitro lipolysis assays often underestimate LBF performance in vivodue to the absence of absorption sink. READ MORE

  3. 2. Effect of lipid-based formulation on the solubilization patterns if poorly water-soluble drugs.

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Manjiri Gude; [2021]
    Keywords : Lipid based formulations LBFs ; poorly water-soluble drugs PWSDs ; solubility studies; coarse grained molecular dynamic simulations; solubilization; dog intestinal fluid DIF ;

    Abstract : Poorly water-soluble drugs (PWSDs), to date, require advanced formulation techniques to improve solubility and achieve the required plasma concentration to show a therapeutic effect when orally administered. Lipid-based formulations (LBFs) are an enabling strategy that is being used to improve the oral delivery of PWSDs. READ MORE