Essays about: "Retinoic acid"

Showing result 1 - 5 of 7 essays containing the words Retinoic acid.

1. 1. Actin filaments as an indicator of impaired neuronal differentiation mediated by disruption of the retinoic acid signalling pathway

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Hanin Salloum; [2022]
   Keywords : Retinoic acid; actin; cytoskeleton; neural progenitor C17.2 cells; neuron; Coronin 1C; Cdc42 Cdc42 effector protein 4 gene ; Fn1 Fibronectin ; Wnt pathway.;

   Abstract : Retinoic acid (RA) is a well-known neurodevelopmental signaling molecule. It is reported to induce effects on neurite formation in differentiating neurons and to interfere with the actin cytoskeleton. Therefore, this project aimed to investigate the mechanisms behind effects of RA on the actin cytoskeleton of developing neurons using the C17. READ MORE

3. 2. Analysis of cellular retinoic acid binding protein 2 expression in dermal fibroblasts; role in non-healing of chronic wounds

   University essay from Örebro universitet/Institutionen för hälsovetenskaper

   Author : Arshi Amjad; [2017]
   Keywords : CRABP2; p16; chronic wound fibroblast; senescent fibroblasts; cellular senes-cence; retinoic acid; non-healing wounds.;

   Abstract : Abstract Chronic, non-healing wounds constitute a massive financial burden on health care system. The healing processes of these wounds and their underlying pathology are only partly understood. READ MORE

4. 3. Differentiation Therapy of Acute Myeloid Leukemia

   University essay from Lunds universitet/Tillämpad biokemi

   Author : Moa Larsson; [2017]
   Keywords : AML; Leukemia; Acute Myeloid Leukemia; Differentiation Therapy; Differentiation; applied biochemistry; tillämpad biokemi; Medicine and Health Sciences; Biology and Life Sciences; Technology and Engineering;

   Abstract : Acute myeloid leukemia (AML) is characterized by a differentiation block in the myeloid lineages of the hematopoiesis. After the success of the all-trans retinoic acid (ATRA) differentiation therapy which overcomes this differentiation block for AML subtype acute promyelocytic leukemia, attempts have been made to find similar therapies for the remaining subtypes. READ MORE

5. 4. Functional investigation of the potential therapeutic target gene DLG2 in an11q-deleted neuroblastoma cell line and effects of 1,25 vitamin D3 and retinoic acid combination treatments

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Sani Jahic; [2016]
   Keywords : DLG2; neuroblastoma; 1; 25 vitamin D3; retinoic acid;

   Abstract : Neuroblastoma as a pediatric tumor develops in the sympathetic nervous system. DLG2 is a gene that encodes a member of the membrane-associated guanylate kinase (MAGUK) family and it resides in the chromosome region 11q. SK-N-AS is a neuroblastoma cell line with 11q deletion and consequently only one copy of the potential tumor suppressor gene DLG2. READ MORE

6. 5. Investigating the Effect of 1,25-Dihydroxyvitamin D3 and Retinoic acid on Viability, Differentiation and Migration in NB69 and T47D cells.

   University essay from Högskolan i Skövde/Institutionen för hälsa och lärande

   Author : Patricia Saxenborn; [2016]
   Keywords : neuroblastoma; breast cancer; retinoic acid; vitamin D; cancer; proliferation; differentiation; migration;

   Abstract : Cancer is a well-known disease that many people encounter in their lifetime. There is constantly research being performed on cancer to find treatments for those types where none has been found, or even find better or more efficient treatments for those cancer types where there already is treatment available. READ MORE