Essays about: "Serine"

Showing result 1 - 5 of 34 essays containing the word Serine.

  1. 1. Effects of phosphorylation on the ADP-ribosylation activity of PARP16

    University essay from Lunds universitet/Kemiska institutionen

    Author : Virginia Martín Cristóbal; [2023]
    Keywords : ADP-ribosylation; Kinases; PARP16; Phosphorylation; UPR biochemistry; Biochemistry; Chemistry;

    Abstract : PARP16/ARTD15 is an intracellular mono-ADP-ribosyltransferase that catalyzes auto- and heteromodification by transfer of a single ADP-ribose moiety. It belongs to the ADP-ribosyltransferase (ART) superfamily. READ MORE

  3. 2. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    University essay from KTH/Proteinvetenskap

    Author : Alexandra Johannesson; [2023]
    Keywords : neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Abstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE

  4. 3. Molecular Mechanisms of Endophilin B1-Bax Macromolecular Complexes in Membrane Permeabilization and Cell Death

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Tobias Kollberg Hedström; [2022]
    Keywords : ;

    Abstract : A crucial step during apoptosis is the accumulation of the pro-apoptotic protein Bax on the mitochondria where it triggers permeabilization of the outer membrane. This causes the release of cytochrome c into the cytosol and is considered a point of no return in programmed cell death. READ MORE

  5. 4. Investigating Minor States of the Oncoprotein N-MYC, with Focus on Proline Cis/Trans Isomerisation using NMR Spectroscopy

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Frida Haugskott; [2021]
    Keywords : Myc; N-Myc; Intrinsically Disordered protein IDP ; Proline; cis-trans isomerisation; minor conformation; NMR; cancer;

    Abstract : MYC is a family of three regulator genes that codes for transcription factors. Expression of Myc proteins from MYC genes is found to be deregulated in 70 % of all cancer forms. The three human homologs C-Myc, N-Myc and L-Myc are mainly associated with cancer in the lymphatic system, nerve tissues and lung cancer, respectively. READ MORE

  6. 5. Role of CDK4/CDK6 inhibitors: Ribociclib, Palbocilcib and Abemacilcib in treatment of metastatic breast cancer

    University essay from Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Author : Nazanin Ghobadpour; [2021]
    Keywords : Breast cancer; cdk4 6 inhibitors; Bröstcancer; cdk4 6 hämmare;

    Abstract : Breast cancer is the most common cancer among women in Sweden and globally. Socio-demographic, genetic and productive factors together with some endogenous and exogenous hormones and lifestyle are some of the risk factors that can cause this type of cancer. READ MORE