Essays about: "THP-1"

Showing result 1 - 5 of 20 essays containing the word THP-1.

  1. 1. Investigating the crosstalk between estrogen receptor beta in colorectal cancer and tumor-associated macrophages

    University essay from KTH/Proteinvetenskap

    Author : Alicia Bodin; [2023]
    Keywords : estrogen; macrophages; colorectal cancer; qPCR; cell culture; östrogen; makrofager; tjocktarmscancer; qPCR; cellodling;

    Abstract : Tjock-och ändtarmscancer (kolorektalcancer) är den tredje vanligaste cancertypen och den näst vanligaste cancer-relaterade dödsorsaken i världen. Östrogen har visat sig ha en skyddande roll mot kolorektalcancer och östrogenreceptor beta är den dominerande östrogenreceptorn i normalt kolonepitel. READ MORE

  3. 2. Influence of Nrf2 Activators and Keap1 Inhibitors on Antioxidative Phenotypes of THP-1-Derived M1 and M2 macrophages: Therapeutic Potential for Systemic Lupus Erythematosus

    University essay from Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Author : Leo Svahn; [2023]
    Keywords : NRF2; KEAP1; THP-1; M1; M2; SLE;

    Abstract : POPULAR SCIENTIFIC SUMMARY Systemic lupus erythematosus (SLE) is not your average disorder. It behaves like a mischievous troublemaker, wreaking havoc throughout the body, causing inflammation that affects multiple organs. READ MORE

  4. 3. The effect of GSK-3 inhibitor SB216763 on the expression and secretion of IL-8 in THP-1 ASC GFP macrophages cells

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Umaimah Hassen; [2022]
    Keywords : ;

    Abstract : Inflammation is a part of the innate immune system. It protects the body against foreign invaders such as bacteria and viruses. Inflammation helps to restore the body by removing harmful stimuli and starting the healing process. READ MORE

  5. 4. The GSK-3 inhibitor has no effect on production of IL-1β in LPS- and Nigericin-stimulated THP-1 macrophages

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Jessica Halan Söderberg; [2022]
    Keywords : ;

    Abstract : Inflammation is the body's natural defense reaction and is known since ancient times. The inflammation is divided into two main phases, acute and chronic inflammation dependent on the process and cellular mechanisms of the inflammation. READ MORE

  6. 5. GSK-3 post-transcriptionally regulates TNF-α biosynthesis in THP-1 macrophages

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Raghad Alghazali; [2022]
    Keywords : ;

    Abstract : Few things are more fascinating than finding new interactions between previously unrelated pathways. Glycogen synthase kinase-3 (GSK-3), a ubiquitous kinase initially known for its role in regulating glycogen metabolism, has recently been found to be an indispensable regulator of the TLR4-mediated inflammatory response. READ MORE